The lung function profile of once-daily tiotropium and olodaterol via Respimat® is superior to that of twice-daily salmeterol and fluticasone propionate via Accuhaler® …

KM Beeh, E Derom, J Echave-Sustaeta… - … obstructive pulmonary …, 2016 - Taylor & Francis
tiotropium + olodaterol improved lung function to a greater extent than twice-daily salmeterol
… of FEV 1 AUC 0–12 and all other measures of lung function. Importantly, superiority in lung …

Effects of tiotropium combined with theophylline on stable COPD patients of group B, D and its impact on small airway function: a randomized controlled trial

X Xiong, L Fan, H Wu, M Zhu, D Cheng - Advances in Therapy, 2018 - Springer
… in patients with COPD. We evaluated the effects of tiotropium and low-dose theophylline on
stable … ) trial [17] showed that tiotropium was more effective than salmeterol in preventing …

… life effectiveness of indacaterol–glycopyrronium after switching from tiotropium or salmeterol/fluticasone therapy in patients with symptomatic COPD: the POWER study

A Kaplan, KR Chapman, SM Anees… - … obstructive pulmonary …, 2019 - Taylor & Francis
… There is insufficient evidence in stable COPD to determine whether treatment step-down
can be safe and/or without reducing patient benefits; treatment step-down should only be …

The effect of indacaterol/glycopyrronium versus tiotropium or salmeterol/fluticasone on the prevention of clinically important deterioration in COPD

AR Anzueto, CF Vogelmeier, K Kostikas… - … of Chronic Obstructive …, 2017 - Taylor & Francis
… in COPD. In this analysis, we compared the effects of different maintenance treatments on
… prevention of clinically important deterioration (CID) in moderate-to-severe COPD patients. …

[HTML][HTML] Efficacy of tiotropium bromide combined with different doses of fluticasone plus salmeterol DPI in the treatment of stable COPD

X Ma, J Xu, J Yang - American Journal of Translational Research, 2021 - ncbi.nlm.nih.gov
… Conclusion: Tiotropium bromide combined with high dose of salmeterol xinafoate (… function
of patients with moderate to severe stable COPD. Keywords: Tiotropium bromide, salmeterol

Impact of tiotropium+ olodaterol on physical functioning in COPD: results of an open-label observational study

R Sauer, M Hänsel, R Buhl, RA Rubin… - … of Chronic Obstructive …, 2016 - Taylor & Francis
tiotropium + olodaterol in a large patient population in a real-world clinical setting. We found
that in a typical outpatient COPD population, tiotropium … The beneficial effects for the primary …

Tiotropium in chronic obstructive pulmonary disease–a review of clinical development

A Anzueto, M Miravitlles - Respiratory research, 2020 - Springer
function, tiotropium did so to a greater extent than salmeterol. … a large proportion of total
COPD burden on the healthcare … reducing COPD exacerbations and treatment of stable COPD

Tiotropium/olodaterol: a review in COPD

HA Blair - Drugs, 2019 - Springer
… Maintenance bronchodilator therapy is key to the management of stable COPD, which aims
to … propionate/salmeterol at improving lung function in patients with moderate to severe …

Tiotropium/olodaterol: a review in COPD

S Dhillon - Drugs, 2016 - Springer
… /salmeterol. Inspiratory capacity and exercise endurance were also improved with …
bronchodilators are key to symptom management in stable COPD, with inhaled therapy preferred …

Efficacy of tiotropium/olodaterol compared with tiotropium as a first-line maintenance treatment in patients with COPD who are naïve to LAMA, LABA and ICS: pooled …

R Buhl, A de la Hoz, W Xue, D Singh, GT Ferguson - Advances in Therapy, 2020 - Springer
… We examined the effect of tiotropium/olodaterol 5/5 µg versus tiotropium 5 µg on trough
FEV 1 response, St. George’s Respiratory Questionnaire (SGRQ) total score and Transition …