Surfactants in acute respiratory distress syndrome in infants and children: past, present and future

A Amigoni, A Pettenazzo, V Stritoni, M Circelli - Clinical drug investigation, 2017 - Springer
… , concluded that the incidence of ALI/ARDS in the USA was … While we know that ALI/ARDS
occurs less often in children … that exogenous surfactant therapy shows greater efficacy while in …

[PDF][PDF] An overview of acute lung injury in general and in particular viral infections with specific reference to nebulized surfactant and anticoagulation

J Smith, JМ Zyl - Am. Rev. Respir. Dis, 2020 - researchgate.net
… suffice, hence our attempt at a targeted functional approach. … New techniques of surfactant
administration in combination … reported in the use of surfactant in ALI/ARDS, we agree with …

Surfactant therapies for pediatric and neonatal ARDS: ESPNIC expert consensus opinion for future research steps

D De Luca, P Cogo, MC Kneyber, P Biban, MG Semple… - Critical Care, 2021 - Springer
… on this, to create a consensus opinion about future research steps in this field. The … on
surfactant biology during ARDS and (2) randomized controlled trials comparing surfactant therapy

Surfactant therapy in the acute respiratory distress syndrome

RG Spragg, JF Lewis - Acute Respiratory Distress Syndrome, 2016 - taylorfrancis.com
… may have future therapeutic application in treatment of … contribute to loss of surfactant function
during the course of ARDS. … Surfactant treatment of patients with ALI/ARDS reduces lung …

Severe COVID-19 ARDS treated by bronchoalveolar lavage with diluted exogenous pulmonary surfactant as salvage therapy: In pursuit of the holy grail?

B Ruaro, P Confalonieri, R Pozzan, S Tavano… - Journal of Clinical …, 2022 - mdpi.com
… in COVID-19 ARDS, providing insights for future research. Methods: … surfactant therapy in
COVID-19 ARDS in our case series. … to patients with ALI/ARDS. One trial showed that synthetic …

… ways of mechanical ventilation combined with pulmonary surfactant in treatment of acute lung injury/acute respiratory distress syndrome in neonates: a comparative …

M Chang, HY Lu, H Xiang, HP Lan - Zhongguo Dang dai er ke za …, 2016 - europepmc.org
… A total of 136 neonates with ALI/ARDS were enrolled, among … The neonates in the first two
groups were given PS at a dose of 70-… To arrive at the top five similar articles we use a word-…

Clinical Utility of the Sivelestat for the Treatment of ALI/ARDS: Moving on in the Controversy?

Q Ding, Y Wang, C Yang, X Li, X Yu - Intensive Care Research, 2023 - Springer
during a few days, which is often manifested as an acute lung injury/acute respiratory distress
syndrome (ALI/ARDS), … In the future, more basic experiments or clinical studies should be …

Circulating Surfactant Protein D: A Biomarker for Acute Lung Injury?

A Elmore, A Almuntashiri, X Wang, S Almuntashiri… - Biomedicines, 2023 - mdpi.com
surfactants is to diminish surface tension in the alveoli at the air–liquid interface and inhibit
its collapse at … current results for SP-D in ALI/ARDS from preclinical and clinical studies. Our …

Acute respiratory distress syndrome: therapeutics, pathobiology, and prognosis

V Vellingiri, P Thirusangu, I Din - … Lung Diseases: Pathophysiology and …, 2020 - Springer
… and highlights areas of future perspectives in therapeutics. … The cuboidal type II AECs
secrete a surfactant that is believed … a causal factor for development of ALI/ARDS [51]. However, …

[HTML][HTML] Endotracheal surfactant combined with budesonide for neonatal ARDS

B Deliloglu, F Tuzun, MM Cengiz, H Ozkan… - Frontiers in …, 2020 - frontiersin.org
… , and during this specific period exogenous surfactant treatment may be considered (11). …
Therefore, we decided to use budesonide combined with surfactant treatment to (i) minimize …