… In conclusion, the genomic landscapes of young-onset and older onset colorectal cancer,
while overall similar, display specific differences in genes that have may prognostic …

… We reported all recurrent AI events for colorectal cancer genes that have been reported
to … in previous genomic annotations of the landscape of colorectal cancers (Supplementary …

… blockade in colorectal cancer. A mutational signature of MMR deficiency has been identified,
but is not commonly noted in breast cancer – either it is uncommon in breast cancer; or its …

… genomic and transcriptomic data and new insights for the molecular mechanism studies of
colorectal cancer… tissues and primary and metastatic colorectal tumors for single-cell RNA-Seq…

… % of colorectal carcinoma, 3.1 5.6 9.2 % of small bowel cancer, 1.3 3.8 8.4 % of ampullary
… distinct genomic landscapes To capture the genomic landscapes of RAS-mutant tumors, we …

… We thus set out to comprehensively explore how mutation signatures in human breast
cancers are influenced by genomic architecture. Critically, we were able to assign probabilistic …

… The identified somatic mutations were compared with those in colorectal cancer (CRC)
samples from The Cancer Genome Atlas. A supervised random forest model was employed to …

… Here, we (i) review the spectrum of genetic alterations that lead to colorectal cancer, (ii)
describe the most frequent copy number alterations at different stages of colorectal …

… : Our study reveals genome landscapes in rectal cancer before and after CRT and tumors
evolution … characteristics are useful for further investigations of CRT resistance in rectal cancer. …

… Colorectal cancer is the 2nd leading cause of cancer-related deaths with few patients
benefiting from biomarker-guided therapy. Mutation expression is essential for accurate …