Comprehensive genomic landscapes in early and later onset colorectal cancer
… In conclusion, the genomic landscapes of young-onset and older onset colorectal cancer,
while overall similar, display specific differences in genes that have may prognostic …
while overall similar, display specific differences in genes that have may prognostic …
Genomic landscape of colorectal mucosa and adenomas
… We reported all recurrent AI events for colorectal cancer genes that have been reported
to … in previous genomic annotations of the landscape of colorectal cancers (Supplementary …
to … in previous genomic annotations of the landscape of colorectal cancers (Supplementary …
The genomic landscape of breast cancer and its interaction with host immunity
… blockade in colorectal cancer. A mutational signature of MMR deficiency has been identified,
but is not commonly noted in breast cancer – either it is uncommon in breast cancer; or its …
but is not commonly noted in breast cancer – either it is uncommon in breast cancer; or its …
Single-cell genomic and transcriptomic landscapes of primary and metastatic colorectal cancer tumors
… genomic and transcriptomic data and new insights for the molecular mechanism studies of
colorectal cancer… tissues and primary and metastatic colorectal tumors for single-cell RNA-Seq…
colorectal cancer… tissues and primary and metastatic colorectal tumors for single-cell RNA-Seq…
Genomic landscapes and hallmarks of mutant RAS in human cancers
… % of colorectal carcinoma, 3.1 5.6 9.2 % of small bowel cancer, 1.3 3.8 8.4 % of ampullary
… distinct genomic landscapes To capture the genomic landscapes of RAS-mutant tumors, we …
… distinct genomic landscapes To capture the genomic landscapes of RAS-mutant tumors, we …
The topography of mutational processes in breast cancer genomes
… We thus set out to comprehensively explore how mutation signatures in human breast
cancers are influenced by genomic architecture. Critically, we were able to assign probabilistic …
cancers are influenced by genomic architecture. Critically, we were able to assign probabilistic …
The somatic mutation landscape of premalignant colorectal adenoma
… The identified somatic mutations were compared with those in colorectal cancer (CRC)
samples from The Cancer Genome Atlas. A supervised random forest model was employed to …
samples from The Cancer Genome Atlas. A supervised random forest model was employed to …
[HTML][HTML] The landscape of genomic copy number alterations in colorectal cancer and their consequences on gene expression levels and disease outcome
… Here, we (i) review the spectrum of genetic alterations that lead to colorectal cancer, (ii)
describe the most frequent copy number alterations at different stages of colorectal …
describe the most frequent copy number alterations at different stages of colorectal …
[HTML][HTML] Genome landscapes of rectal cancer before and after preoperative chemoradiotherapy
J Yang, Y Lin, Y Huang, J Jin, S Zou, X Zhang, H Li… - Theranostics, 2019 - ncbi.nlm.nih.gov
… : Our study reveals genome landscapes in rectal cancer before and after CRT and tumors
evolution … characteristics are useful for further investigations of CRT resistance in rectal cancer. …
evolution … characteristics are useful for further investigations of CRT resistance in rectal cancer. …
The expressed mutational landscape of microsatellite stable colorectal cancers
A Sveen, B Johannessen, IA Eilertsen, BI Røsok… - Genome Medicine, 2021 - Springer
… Colorectal cancer is the 2nd leading cause of cancer-related deaths with few patients
benefiting from biomarker-guided therapy. Mutation expression is essential for accurate …
benefiting from biomarker-guided therapy. Mutation expression is essential for accurate …