Neuroprotection through G-CSF: recent advances and future viewpoints

V Rahi, S Jamwal, P Kumar - Pharmacological Reports, 2021 - Springer
… , G-CSF reduces the glutamate-induced neuronal cell death and … G-CSF is a hematopoietic
growth factor which mobilize … In compilation, the G-CSF is the potent neural ligand and …

Turning death to growth: hematopoietic growth factors promote neurite outgrowth through MEK/ERK/p53 pathway

M Gao, LR Zhao - Molecular neurobiology, 2018 - Springer
… and G-CSF have been found to express in the neural stem cells/neural progenitor cells (…
the combination of two hematopoietic growth factors, SCF + G-CSF, synergistically activates the …

Hematopoietic stem cell mobilization

HH Chang, YS Liou, DS Sun - Tzu Chi Medical Journal, 2022 - journals.lww.com
… The interaction between Notch2 and its ligand also maintains HSC … G-CSF activates the
sympathetic neurons innervating BM by … FGF-23 can counteract the function of CXCR4 and then …

New insight into the mechanism of granulocyte colony-stimulating factor (G-CSF) that induces the mobilization of neutrophils

A Theyab, M Algahtani, KF Alsharif, YM Hawsawi… - …, 2021 - Taylor & Francis
… The ability of G-CSF to mobilize hematopoietic stem cells … of G-CSF exerts neuroprotective
effects on damaged neurons … Each ligand of G-CSF interacts with the CRH domain of one G-…

Role of Granulocyte-Colony Stimulating Factor (G-CSF) in Immune Regulation and Neuroprotection

J Dumbuya, H Prentice, JY Wu - Journal of Cellular …, 2023 - scientificarchives.com
… the numbers of hematopoietic stem/progenitor cells in patients … of G-CSF in neuronal protection
since it protects neurons … found additional up-regulated ligand-receptor pairs enriched in …

Colony stimulating factors in the nervous system

V Chitu, F Biundo, ER Stanley - Seminars in immunology, 2021 - Elsevier
… regulators of hematopoiesis, colony-stimulating factors (CSFs) … This review summarizes the
cellular sources, patterns of … ) and granulocyte (G-CSF) colony stimulating factors within the …

Antiapoptotic effect of granulocyte-colony stimulating factor after peripheral nerve trauma

D Keiner, JP Kühn, A Huber, J Oertel - World Neurosurgery, 2019 - Elsevier
G-CSF and the G-CSF receptor (G-CSFR) in hematopoieticG-CSF diminishes neuronal
destruction and neuronal death … exact time course of neuronal programmed cell death, onset, …

The Combination of Stem Cell Factor (SCF) and Granulocyte-Colony Stimulating Factor (G-CSF) in Repairing the Brain Post-acute Stroke

LR Zhao, S Ping, F Hao - Cellular and Molecular Approaches to …, 2018 - Springer
… of SCF and G-CSF in hematopoiesis, neural plasticity, and … only because of the enhanced
ligand/receptor interaction [76]… increases the number of cell death and results in thinning of …

G-CSF in tumors: Aggressiveness, tumor microenvironment and immune cell regulation

I Karagiannidis, E Salataj, ESA Egal, EJ Beswick - Cytokine, 2021 - Elsevier
… is also expressed in other tissues such as the placenta, adult neural stem cells, B-cells and
hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death

Delayed application of the haematopoietic growth factors G-CSF/SCF and FL reduces neonatal excitotoxic brain injury

V Neubauer, K Wegleiter, A Posod, M Urbanek… - Brain research, 2016 - Elsevier
factor (G-CSF), stem cell factor (SCF) and flt-3 ligand (FL) on … typical cortical lesions
with large neuronal loss in all cortical … cell death, we primarily investigated the effect of G-CSF/SCF …