… GIRK channels are members of a family of inwardly rectifying … of histamine receptors in
Xenopus Laevis oocytes, human H1… to couple with the inward rectifier potassium channels GIRK1/…

Histamine H3 Receptor Activation Modulates Glutamate … IR 3 channels has been shown
in Xenopus oocytes upon the … of the GIRK channels present in the corticostriatal terminals. …

… The human histamine H 3 receptor (hH 3 R) is a neurotransmitter receptor in the central
nervous system (CNS) [1] that has been a longstanding drug target for various CNS disorders, …

… propyl-spaced analogues was also observed for the pairs 14/15 and 16/17. Derivatives with
… we superfused Xenopus oocytes expressing H 3 R and a GIRK channel with histamine and …

… -clamp in Xenopus oocytes heterologously expressing GPCRs … response in oocytes expressing
GIRK channels without D 1 … R has previously been reported to couple to PTX-sensitive G …

… to couple receptor … Xenopus oocytes [Citation34], the measurement of K + currents, generated
by Gβγ complexes acting at G protein-coupled inward rectifier potassium channels (GIRKs)…

… We developed a set of sixteen photoswitchable ligands for the human histamine H3 receptor
(… The human histamine H3 receptor couples to GIRK channels in Xenopus oocytes. Eur. J. …

… receptors has been shown both in vitro (human, pig, guinea-pig, rabbit, rat isolated tissues)
and in vivo (rat, guinea-pig)[21].Histamine H3 receptors … [25-26]Histamine H3 receptor can …

… (GIRK) channels are an integral part of inhibitory signal transduction pathways. Opening of
GIRK channels … nm light allowing for reversible control over H3 receptors in Xenopus oocytes. …

… In the thesis, M2R, D2R and D3R were investigated using two-electrode voltage-clamp in
Xenopus laevis oocytes co-expressing the respective receptor and GIRK channels. M2R …