… Histone modifications including acetylation, methylation, ubiquitination and phosphorylation
are important players in the regulation of gene expression within the TME. It has been …

… on how tumor microenvironment metabolically instructs immune responsiveness. … Cancers
are highly heterogeneous, and a broad spectrum of immune cells can infiltrate human tumor …

… results, playing with the immune system raised important issues in … the major sub-populations
of inhibitory immune cells that are frequently found in several mouse and human cancers …

… This review provides an overview on the HCC immune microenvironment, different cellular
players, current available immunotherapies, and potential immunotherapy modalities. …

… Using bulk or single-cell data on CAFs from human cancers and mouse models, the
existence of ECM-rich (CAF-S1) and contractile (CAF-S4) subpopulations of CAFs was further …

… ) are key players in tumorigenesis and immune responses. … functions in the tumor immune
microenvironment (TIME). To … specifically expressed in tumor and immune cells, summarize …

… immuno-metabolism plays a leading role both in the tumor microenvironment (TME) and at
the host level. In this review, we summarize the most important immune-metabolic factors and …

… microenvironment of human tumors, and typically, PMN-MDSCs represent more than 80% of
all tumor… these cells are central players in the tumor microenvironment, serving as signaling …

… Recent studies suggest that CSCs are pivotal players in immune escape: due to their …
further studies are warranted to determine if they behave the same way in human cancers. …

… immunity, and promote progression of HCC [10, 11]. The magnitude of immune suppression
in the tumor microenvironment … cells of HCC, here, we summarize the representative players …