Dynamic interactions between tumor cells and brain microvascular endothelial cells in glioblastoma

E Testa, C Palazzo, R Mastrantonio, MT Viscomi - Cancers, 2022 - mdpi.com
… VEGF provides not only paracrine survival cues for BMECs, … by direct cell contact (gap
junction) or by paracrine signaling. … by direct cell contact (gap junction) or by paracrine signaling. …

Human neural stem cell-induced endothelial morphogenesis requires autocrine/paracrine and juxtacrine signaling

CH Chou, M Modo - Scientific reports, 2016 - nature.com
… mechanisms between human NSCs and endothelial cells (… network being associated with
better NSC survival 10 . There is also an … The roles of paracrine signaling factors in generating …

Transcriptomic Analysis of Human Brain-Microvascular Endothelial Cell Driven Changes in-Vascular Pericytes

L Kurmann, M Okoniewski, RK Dubey - Cells, 2021 - mdpi.com
… BBB integrity and cell survival during infection and … two cell types by paracrine signaling
involves soluble factors such as transforming growth factor beta (TGF-β), vascular endothelial

Endothelial progenitor cells and neural progenitor cells synergistically protect cerebral endothelial cells from Hypoxia/reoxygenation-induced injury via activating the …

J Wang, Y Chen, Y Yang, X Xiao, S Chen, C Zhang… - Molecular brain, 2016 - Springer
… The PI3K/Akt signal pathway participates in various cellular processes such as cell
survival … benefits in protecting brain ECs against H/R injury by VEGF and BDNF paracrine-mediated …

Endothelial Progenitor Cell-Derived Microvesicles Promote Angiogenesis in Rat Brain Microvascular Endothelial Cells In vitro

W Zeng, Q Lei, J Ma, S Gao, R Ju - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
cell-free strategy has been proposed as an alternative to cell transplantation based on the
observation that paracrine signals … were shown to enhance EC survival, morphogenesis, and …

Inflammatory environment promotes the adhesion of tumor cells to brain microvascular endothelial cells

K Wang, S Dong, D Higazy, L Jin, Q Zou… - Frontiers in …, 2021 - frontiersin.org
… metastasis tumors and TNF-α stimulated cells. To verify these results, we used a mixed
culture of lung tumor cells (A549 and H358) with brain microvascular endothelial cells (HBMECs) …

Pericyte-endothelial interactions in the retinal microvasculature

H Huang - International journal of molecular sciences, 2020 - mdpi.com
… and endothelial cells (ECs) are the two main cellular … and paracrine signaling pathways,
such as Vascular endothelial … , where they modulate cell survival induced by pulsatile flow …

[HTML][HTML] Intervention of exogenous VEGF protect brain microvascular endothelial cells from hypoxia-induced injury by regulating PLCγ/RAS/ERK and PI3K/AKT …

J Wang, X Wu, J Fang, Q Li - Experimental Gerontology, 2024 - Elsevier
… by most parenchymal cells and acts in a paracrine manner on adjacent endothelial … under
hypoxic conditions and exerts pro-survival and proliferative effects on brain microvascular

Glioblastoma stem cells microenvironment: the paracrine roles of the niche in drug and radioresistance

A Fidoamore, L Cristiano, A Antonosante… - Stem cells …, 2016 - Wiley Online Library
… The laminin receptor integrin α6β1 has been shown to regulate tumor cell survival,
promoting endothelial cell growth in GBM [170]. Laminin is also important in the laminin-integrin …

The effect of normoxic and hypoxic U-87 glioblastoma paracrine secretion on the modulation of brain endothelial cells

M Rado, B Flepisi, D Fisher - Cells, 2022 - mdpi.com
… GBM patients have a median overall survival of approximately 15 months [7] and … the effect
of glioblastoma-secreted paracrine factors on the physiological state of brain endothelial cells