Apolipoprotein E in lipoprotein metabolism, health and cardiovascular disease

AD Marais - Pathology, 2019 - Elsevier
… lipoprotein concentration and the risk of atherosclerosis. ApoE2 generally is most favourable
… More recently, its important role at the cellular level has been elucidated in the provision of …

Apolipoprotein E, periodontal disease and the risk for atherosclerosis: a review

LC Pereira, JCR Nascimento, JMC Rêgo… - Archives of Oral …, 2019 - Elsevier
Apolipoprotein E (ApoE = protein; APOE = gene) is a glycoprotein synthesized in the liver that
plays a key role … In addition, ApoE plays a pivotal role in different inflammatory conditions (…

[HTML][HTML] Apolipoprotein E and atherosclerosis: from lipoprotein metabolism to MicroRNA control of inflammation

L Bouchareychas, RL Raffai - Journal of cardiovascular development and …, 2018 - mdpi.com
… κB–driven inflammation and atherosclerosis in hyperlipidemic … for apoE in its capacity to
suppress atherosclerosis beyond … Beyond its pivotal role in regulating lipoprotein cholesterol …

Emerging roles of apolipoprotein E and apolipoprotein AI in the pathogenesis and treatment of lung disease

X Yao, EM Gordon, DM Figueroa… - American journal of …, 2016 - atsjournals.org
… in the lung by apolipoprotein E (apoE) and apolipoprotein AI (apoA-I). ApoE mediates the
cellular … In addition to its important role in the prevention of atherosclerosis, apoA-I modulates …

[HTML][HTML] Apolipoprotein E: structural insights and links to Alzheimer disease pathogenesis

Y Chen, MR Strickland, A Soranno, DM Holtzman - Neuron, 2021 - cell.com
Apolipoprotein E (ApoE) is of great interest due to its role as a cholesterol/lipid transporter
in the central nervous … In addition to the critical role that ApoE plays in peripheral cholesterol …

Cell-specific production, secretion, and function of apolipoprotein E

M Kockx, M Traini, L Kritharides - Journal of molecular medicine, 2018 - Springer
… of apoE can inhibit atherosclerosis without affecting … crucial in maintaining brain integrity
and homeostasis. Studies using the apoE knockout mouse indicated an important role of apoE

[HTML][HTML] Adiponectin improves NF-κB-mediated inflammation and abates atherosclerosis progression in apolipoprotein E-deficient mice

X Wang, Q Chen, H Pu, Q Wei, M Duan… - Lipids in health and …, 2016 - Springer
… Male ApoE -/- mice aged 12 weeks were used in this study as animal model of
atherosclerosis. All procedures related to the animal experiments were approved (IACUC-20130709010) …

Quercetin attenuates high fat diet-induced atherosclerosis in apolipoprotein E knockout mice: A critical role of NADPH oxidase

L Xiao, L Liu, X Guo, S Zhang, J Wang, F Zhou… - Food and Chemical …, 2017 - Elsevier
… Our findings suggest that regular consumption of dietary quercetin plays a role in
preventing atherosclerosis giving its evident regulatory effect on subunits of NADPH oxidase. …

Apolipoprotein E in cardiovascular diseases: novel aspects of an old-fashioned enigma

EA Liehn, V Ponomariov, R Diaconu, I Streata… - Archives of medical …, 2018 - Elsevier
… Nevertheless, knowing the role of APOE in atherosclerosis has helped the researchers to …
face regarding APOE effects on immune cells, known to play a decisive role in atherosclerotic

[HTML][HTML] The role of lipids and lipoproteins in atherosclerosis

MRF Linton, PG Yancey, SS Davies, WG Jerome… - Endotext …, 2019 - ncbi.nlm.nih.gov
role of lipids and lipoproteins in the pathogenesis of atherosclerosis as well as their critical
roles … The recognition that atherosclerosis is an inflammatory disease has led to tremendous …