Neutrophilic inflammation in the pathogenesis of chronic obstructive pulmonary disease

A Butler, GM Walton, E Sapey - … Obstructive Pulmonary Disease, 2018 - Taylor & Francis
… Current paradigms of chronic obstructive pulmonary disease (… the progression of the disease
in the long term. More treatment … are implicated in COPD, the neutrophil is by far the most …

Inflammatory mechanisms in patients with chronic obstructive pulmonary disease

PJ Barnes - Journal of Allergy and Clinical Immunology, 2016 - Elsevier
… EGFRs play an important role on mucus hyperplasia and secretion and can be activated by
neutrophilic inflammation through neutrophil elastase secretion, which releases TGF-α (Fig 2)…

[HTML][HTML] Neutrophil extracellular traps are associated with disease severity and microbiota diversity in patients with chronic obstructive pulmonary disease

AJ Dicker, ML Crichton, EG Pumphrey… - Journal of Allergy and …, 2018 - Elsevier
Neutrophil extracellular traps (NETs) have been observed in the airway in patients with
chronic obstructive pulmonary disease (COPD), but their clinical and pathophysiologic …

Role of neutrophil extracellular traps in asthma and chronic obstructive pulmonary disease

T Liu, FP Wang, G Wang, H Mao - Chinese medical journal, 2017 - mednexus.org
airway diseases. In the airways of asthmatic and chronic obstructive pulmonary disease
patients, neutrophils can be stimulated by a variety of biological molecules (eg., interleukin-8 [IL-…

The neutrophil to lymphocyte ratio is related to disease severity and exacerbation in patients with chronic obstructive pulmonary disease

R Furutate, T Ishii, T Motegi, K Hattori, Y Kusunoki… - Internal …, 2016 - jstage.jst.go.jp
… Objective Although chronic obstructive pulmonary disease (COPD) is characterized by
systemic inflammation, the association between the neutrophil to lymphocyte ratio (NLR; an …

[HTML][HTML] Usefulness of neutrophil to lymphocyte ratio in patients with chronic obstructive pulmonary disease: a prospective observational study

SJ Lee, HR Lee, TW Lee, S Ju, S Lim… - The Korean journal of …, 2016 - ncbi.nlm.nih.gov
Neutrophil to lymphocyte ratio (NLR) in peripheral blood is a useful systemic inflammatory
… However, NLR has not been studied in patients with chronic obstructive pulmonary disease (…

Alterations of the neutrophil–lymphocyte ratio during the period of stable and acute exacerbation of chronic obstructive pulmonary disease patients

M Taylan, M Demir, H Kaya… - … clinical respiratory …, 2017 - Wiley Online Library
… We aimed to investigate the importance of neutrophil–lymphocyte ratio (NLR) in patients
with chronic obstructive pulmonary disease (COPD) for identifying the severity of inflammation …

[HTML][HTML] Association of the neutrophil-to-lymphocyte ratio with lung function and exacerbations in patients with chronic obstructive pulmonary disease

H Lee, SJ Um, YS Kim, DK Kim, AS Jang, HS Choi… - PloS one, 2016 - journals.plos.org
… The ratio of neutrophils to lymphocytes (… chronic obstructive pulmonary disease (COPD).
We sought to evaluate the association of the NLR with severity of airflow limitation and disease

Our evolving view of neutrophils in defining the pathology of chronic lung disease

KT Mincham, N Bruno, A Singanayagam… - …, 2021 - Wiley Online Library
neutrophilic inflammation is a hallmark feature of patients with chronic lung diseases such
as chronic obstructiveobstructive pulmonary disease (COPD) and cystic fibrosis (CF) [5]. …

The neutrophil‐to‐lymphocyte ratio as a marker of chronic obstructive pulmonary disease and its exacerbations: A systematic review and meta‐analysis

P Paliogiannis, AG Fois, S Sotgia… - European Journal of …, 2018 - Wiley Online Library
… , neutrophils and lymphocytes, are involved in the pathophysiology of chronic obstructive
pulmonary disease (… investigating the relationship between the neutrophil to lymphocyte ratio (…