… and fatal interstitial lung disease. During the past decade, novel pathogenic mechanisms of
… extracellular matrix accumulation result in pulmonary fibrosis. Although there is currently no …

… involved in the pathogenesis of pulmonary fibrosis, of which TGF-β is particularly potent [6],
[8], [9]. Tyrosine kinases have been shown to play a critical role in the pathogenesis of IPF [13…

… pulmonary fibrosis pathogenesisꎬ prognosisꎬ and treatment[… Cellularmechanismsoftissue
fibrosis. 7. New insights into the … pulmonary fibrosis[J]. Int J Mol Sciꎬ 2015ꎬ 16:21486-21519. …

… comprises a much more diverse group, commonly distinguished from LS by insidious onset,
slow progression and a higher risk of developing chronic disease and pulmonary fibrosis. …

… These data suggest that glycolytic reprogramming is important in the pathogenesis of lung
fibrosis and therefore represents a potential therapeutic target. More research is needed in …

… main targets for treatment of pulmonary fibrosis (… pulmonary fibrosis (205, 206). Studies
have demonstrated that targeting TGF-β1 by monoclonal antibodies reduced pulmonary fibrosis …

… species (ROS) in the pathogenesis of idiopathic pulmonary fibrosis. Nox4 has also been
found to be upregulated in mouse models of IPF and in lung fibroblasts of human IPF patients. …

… pathogenesis of pulmonary fibrosis can be associated with a variety of other disorders (ie,
pulmonary … Results of the study suggested miR-26a as a novel target for IPF prevention and …

… Pulmonary fibrosis is a chronic and fatal lung disease that significantly impacts the aging
population globally. To date, anti-fibrotic, … of the pathogenic mechanisms of lung fibrosis will …

… treatment of idiopathic pulmonary fibrosis, as well as all active and completed phase 2 and
3 clinical trials of nintedanib and pirfenidone for the treatment … of pulmonary fibrosis and lung …