Endoglin regulates mural cell adhesion in the circulatory system

E Rossi, DM Smadja, E Boscolo, C Langa… - Cellular and Molecular …, 2016 - Springer
Endoglin is highly expressed by ECs during neoangiogenic processes at the same time as
… a critical physiological role in the cardiovascular system [21]. Mutations in the endoglin gene …

Endoglin: beyond the endothelium

MJA Schoonderwoerd, MJTH Goumans… - Biomolecules, 2020 - mdpi.com
role of endoglin in innate and adaptive immunity. Finally, we will discuss the results of clinical
trials using the endoglin … and subsequently released into the circulation system. This might …

[HTML][HTML] Novel vascular roles of human endoglin in pathophysiology

E Rossi, C Bernabeu - Journal of Thrombosis and Haemostasis, 2023 - Elsevier
… Basal endoglin expression levels vary in the vascular endothelium of different tissues,
whereas they are clearly upregulated in ECs from inflamed tissues with an associated …

Membrane and soluble endoglin role in cardiovascular and metabolic disorders related to metabolic syndrome

M Vicen, IC Igreja Sá, K Tripská, B Vitverová… - Cellular and Molecular …, 2021 - Springer
… idiopathic or hereditary PAH, PAH associated with connective tissue disease, drug, or
toxin-related PAH, but not with PAH related to congenital heart disease [17]. Also, Coral-Alvarado …

Endoglin/CD105-based imaging of cancer and cardiovascular diseases: a systematic review

VQ Sier, JR van der Vorst, PHA Quax… - International journal of …, 2021 - mdpi.com
… 64 Cu-NOTA-TRC105-(Fab) has been employed in three different cardiovascular disease
models to achieve endoglin-based PET imaging: murine hindlimb ischemia, rat myocardial …

The role of endoglin in post-ischemic revascularization

E Núñez-Gómez, M Pericacho, C Ollauri-Ibáñez… - Angiogenesis, 2017 - Springer
… is composed of the vascular endothelium and mural cells. The vascular endothelium is a
cell monolayer that lines all blood-contacting surfaces in the circulatory system. Its strategic …

Endoglin as an adhesion molecule in mature and progenitor endothelial cells: a function beyond TGF-β

E Rossi, C Bernabeu, DM Smadja - Frontiers in medicine, 2019 - frontiersin.org
… cell types present in the circulatory system have also revealed … the role of endoglin in ECs,
it is worth mentioning that endoglin … However, a review on the endoglin role in these cell types …

Dynamic changes in endoglin expression in the developing mouse heart

E Singh, HM Phillips, HM Arthur - Gene Expression Patterns, 2021 - Elsevier
Endoglin (ENG) is essential for cardiovascular development and is expressed in the heart
ENG expression has been reported in the cardiac crescent, endocardium, valve mesenchyme …

The clinical significance of endocardial endothelial dysfunction

S Smiljic - Medicina, 2017 - mdpi.com
… Preserving the endocardial-myocardial integrity plays a significant role in the prevention
of a coronary artery disease. Endocardial endothelial dysfunction is, similarly to coronary …

Potential role of circulating endoglin in hypertension via the upregulated expression of BMP4

E Gallardo-Vara, L Gamella-Pozuelo, L Perez-Roque… - Cells, 2020 - mdpi.com
… defects, suggesting a key role of endoglin in the vascular system [11]. Endoglin is a 180-kDa …
The juxtamembrane region of the endoglin ectodomain can be proteolytically targeted by …