… complex, that is, a multi-protein complex recruited to chromatin by DNA bound repressor
proteins to facilitate local histone deacetylation … of the physiological roles of Sin3 complexes in …

… Kelly, RD & Cowley, SM The physiological roles of histone deacetylase (HDAC) 1 and 2:
complex co-stars with multiple leading parts. Biochemical Society transactions 41, 741–749, …

… HDACs and, thereby, regulates their many functions under various cellular and physiological
… Class I HDACs are members of different co-repressor complexes, which augment their …

… complexes [2]. HDAC3 is somewhat more distantly related to HDAC1 and HDAC2 and is
found in a distinct multi… used to study the CoREST complex's physiological functions, targets, …

… complex composed of two H2A/H2B dimers and one H3/H4 tetramer, while the linker …
HDACs can exert direct effects on physiological processes such as apoptosis, differentiation…

… Histone deacetylase (HDAC) enzymes play crucial roles in … are controlled by two opposing
families of enzymes: histone … as part of a multi-subunit co-repressor complex in vivo and is …

… Histone deacetylases (HDACs) 2 play important roles in the … HDAC inhibitors (HDACi) 3
that act on multiple HDAC enzymes … , HDACs 1 and 2 function within multi-protein complexes …

… multi subunit complexes that contain HDACs1 and 2, but differ in the composition of the other
subunits. HDACs 1 and 2 … with HDAC complexes, favours the removal of histone acetylation …

… mainly by influencing a broad range of physiological processes. … Histone acetylation is
accomplished by two enzymes: … or more HDAC isoforms in multiprotein complexes (13, 14). …

… HDAC3 shares only about 50% amino acid identity with HDAC1 and HDAC2 and binds
to two distinct complexes containing nuclear receptor co-repressors NCOR1 and NCOR2 (also …