[HTML][HTML] Intracerebroventricular administration of L-arginine improves spatial memory acquisition in triple transgenic mice via reduction of oxidative stress and …

G Fonar, B Polis, T Meirson, A Maltsev… - Translational …, 2018 - degruyter.com
Amyloid β peptide (25-35) was dissolved in mQ water to 1 … L-Arginine does not rescue impaired
by Aβ hippocampal long… the 3xTg-AD mouse model, without altering the amyloid aspects …

Molecular mechanisms of neurodegeneration in the entorhinal cortex that underlie its selective vulnerability during the pathogenesis of Alzheimer's disease

OJ Olajide, ME Suvanto, CA Chapman - Biology Open, 2021 - journals.biologists.com
… is thought to mediate much of the cognitive impairment … capacity, ROS can disrupt the redox
balance and result in oxidative … In the EC, but not the hippocampus, 3xTg-AD mice show the …

Quercetin Exerts Differential Neuroprotective Effects Against H2O2 and Aβ Aggregates in Hippocampal Neurons: the Role of Mitochondria

JA Godoy, CB Lindsay, RA Quintanilla… - Molecular …, 2017 - Springer
Amyloid-β peptide (Aβ) is one of the major players in the … in the triple transgenic mouse
AD model (3xTg-AD). In this … that the impairment in vesicular release in transgenic mice may …

[HTML][HTML] Capacitive Electrode-Based Electric Field Treatments on Redox-Toxic Iron Deposits in Transgenic AD Mouse Models: The Electroceutical Targeting of …

Y Choi, WS Lee, J Lee, SH Park, S Kim, KH Kim… - International Journal of …, 2023 - mdpi.com
… AD mice demonstrated clearly impaired memory function … aggregates in 5xFAD and 3xTG
AD mouse models using electric … stimulates deep brain tissue in the AD mouse brain, thereby …

Effect of global brain ischemia on amyloid precursor protein metabolism and expression of amyloid-degrading enzymes in rat cortex: role in pathogenesis of …

E Babusikova, D Dobrota, AJ Turner… - Biochemistry (Moscow …, 2021 - Springer
… of two main protein clusters of amyloid β peptide (Aβ) (… number of amyloid plaques in the
brain of transgenic mice modelling … to impaired brain circulation and ischemic conditions in the …

[HTML][HTML] Brain metabolic alterations in Alzheimer's disease

CG Ardanaz, MJ Ramírez, M Solas - International journal of molecular …, 2022 - mdpi.com
… constitutively located in the cell membrane, implying that they … two AD mouse models, ie,
APP/PS1 and 3xTg-AD, EAAT2 … Impaired brain bioenergetics appears to be a central hallmark …

Near infrared light to promote synaptic resilience to Alzheimer's Disease neuropathology

M Comerota - 2018 - utmb-ir.tdl.org
… including oligomer formed pores in the cell membrane (Lai … and brain slices of previously
NIR light treated wild type mice. … (Tg2576) and htau mice and female 3xTgAD mice were …

[HTML][HTML] The emerging role of altered cerebellar synaptic processing in Alzheimer's disease

E Hoxha, P Lippiello, F Zurlo, I Balbo… - Frontiers in aging …, 2018 - frontiersin.org
… motor impairment has been also observed in transgenic mice … in a broad variety of brain
processes, including attention, arousal… The redox metal accumulation affects PCs less than other …

Physical Exercise as a Preventive and Therapeutic Strategy Against Behavioral Dysfunction in Alzheimer's Disease

T Bernardo - 2019 - search.proquest.com
… (SP) mainly composed of amyloid β peptide (Aβ) and … final destination in the plasma
membrane through a secretory … in a female triple transgenic Alzheimer's mice (3xTg-AD) model. …

[HTML][HTML] Alterations of the Sympathoadrenal Axis Related to the Development of Alzheimer's Disease in the 3xTg Mouse Model

A Muñoz-Montero, R de Pascual, A Sáez-Mas… - Biology, 2022 - mdpi.com
… adrenal gland of 3xTg AD model mice to characterize potential … their expression in the cell
membrane, immunohistochemistry … In conclusion, an impairment in the sympathoadrenal axis …