Targeting steroid hormone receptors for anti‐cancer therapy—a review on small molecules and nanotherapeutic approaches

N Mahadik, D Bhattacharya… - Wiley …, 2022 - Wiley Online Library
receptor (GR) is one such exciting SHR that in spite of it being expressed ubiquitously in all
cells, we discovered it to behave differently in cancer … the immense potential that cancer cell-…

The role of sex hormones and steroid receptors on female reproductive cancers

LG de Almeida Chuffa, LA Lupi-Júnior, AB Costa… - Steroids, 2017 - Elsevier
… by which different steroid receptors are potentially involved in the development of OC. …
different steroid hormone receptor family members (ie PR and AR) and glucocorticoid receptor (GR…

A look at current and potential treatment approaches for hormone receptor‐positive, HER2‐negative early breast cancer

N Harbeck, HJ Burstein, SA Hurvitz, S Johnston… - Cancer, 2022 - Wiley Online Library
HORMONE RECEPTOR- POSITIVE BREAST CANCERS Hormone receptor (HR)-
positive breast cancers make up a highly heterogeneous group of malignancies. These malignancies …

[HTML][HTML] Steroid hormone receptors as prognostic markers in breast cancer

MC Louie, MB Sevigny - American journal of cancer research, 2017 - ncbi.nlm.nih.gov
receptor family but is instead a G-protein coupled receptor that … the role of steroid hormone
receptors in breast cancer, GPR-… a potential therapeutic target for those breast cancer patients …

Hormone receptors in serous ovarian carcinoma: prognosis, pathogenesis, and treatment considerations

IA Voutsadakis - Clinical Medicine Insights: Oncology, 2016 - journals.sagepub.com
… further development of these treatments in ovarian cancer. In … profiles instead of treating
all ovarian cancers as a uniform … GnRH receptor are also potential targets of hormone agents …

[HTML][HTML] Hormone signaling pathways as treatment targets in renal cell cancer

AM Czarnecka, M Niedzwiedzka… - International …, 2016 - spandidos-publications.com
… renal cell cancer (RCC) etiology is hormone-related. It was shown that hormone receptors
are abnormally … A possible correlation between 1,25-(OH)2D3 receptor expression in primary …

Treatment of breast cancer with gonadotropin-releasing hormone analogs

M Huerta-Reyes, G Maya-Núñez… - Frontiers in …, 2019 - frontiersin.org
… a group of tumors that do not express either hormone receptors (ER–, PR–) or HER2 receptor
(HER2… (LHRH-R), have been predicted as potentially therapeutic agents for their antitumor …

The molecular function and clinical role of thyroid stimulating hormone receptor in cancer cells

YD Chu, CT Yeh - Cells, 2020 - mdpi.com
hormone receptor (TSHR) is a receptor for thyrostimulin and thyroid stimulating hormone (TSH, …
Additionally, we discuss potential new therapeutic strategies devised according to these …

Cannabinoids and hormone receptor-positive breast cancer treatment

L Dobovišek, F Krstanović, S Borštnar, N Debeljak - Cancers, 2020 - mdpi.com
… known and possible interactions between cannabinoids and specific HR+ BC treatments. In
… cannabinoids on HR+ BC treatment outcomes. Two studies have shown that tamoxifen and …

[HTML][HTML] Role of hormone receptors and HER2 as prospective molecular markers for breast cancer: An update

SS Mohanty, CR Sahoo, RN Padhy - Genes & diseases, 2022 - Elsevier
… therapy is the best therapeutic intervention for hormone receptor-positive cancer, since
those are structurally similar to influencing hormone and block the site on receptors. …