… Since the majority of islet-specific CD4 + T cells in NOD mice … (PE) and allophycocyanin
(APC) in medium containing Fc … activation (CD44) and greater ability to traffic to tissues with …

… mTOR pathway to preferentially promote naive T cells to become … could be overcome in
transgenic NOD mice expressing a … the cells with the following antibodies: anti-CD11c-APC-Cy7 (…

… The preferential ability of B lymphocytes to act as diabetogenic APC in NOD mice depends
on expression of self-antigen-specific immunoglobulin receptors. Eur J Immunol 2002;32:…

… Insulin specific T cells in NOD mice are capable of recognizing … Antigen specificities of
diabetogenic T cells have been a focus … To further determine the ability of insulin-specific T cells to …

… on T cells. Signaling through OX40 has been shown to play an important role in effector T
cell … Treatment of 12-week-old NOD mice resulted in rapid onset of hyperglycemia and an …

… that norovirus can protect NOD mice from T1D development by … The cultured cells were also
used for T cell and APC … of local B cells, we investigated the phenotype of B cells in PP and …

… and expansion of diabetogenic effector T cells (Teff). For … APC that in turn prime β cell-specific
T cells providing an “environmental trigger” to incite T1D development (48). NOD mice in …

… development of TID in NOD mice despite a reported affinity … affects the B cell’s ability to
drive diabetogenic processes, … APC functionality is not due simply to the presence of B cells. …

… The present study demonstrated the ability of butyrate to … tolerance could prevent the
diabetogenic T cells from entering the … T cells transferred from MLN of pre-diabetic NOD mice into …

… Diabetogenic CD4 + and CD8 + T cells target several β cell … T cells and antigen-presenting
cells (APC). Although β … IL-10-producing B cells in the pancreas of NOD mice after treatment (…