… SatMs) to initiate pulmonary fibrosis distinct from the conventional growth factors-driven
fibrosis pathway [91]. Also, the potential beneficial role of chemokines which predominate in Th1 …

… Idiopathic pulmonary fibrosis (IPF) is a fatal chronic interstitial lung … that chemokines are
important regulators of immune responses and fibrogenesis in the context of pulmonary fibrosis, …

… Here, we review the roles of different CC chemokines in the pathogenesis of IPF, and their …
CC chemokines and CXC chemokines in lung tissues, suggesting that these chemokines may …

… C and D: representative Masson’s trichrome stain and semiquantitative fibrosis score
illustrating degree of pulmonary fibrosis in control versus mCXCR2 mice, either Veh and Bleo …

… that chemokines may become new targets for the treatment of many diseases. Here, we
review the role of key CXC … KEYWORDS pulmonary fibrosis; CXC chemokine; CXC chemokine …

… and discuss the role of immune cells (T cells, neutrophils, macrophages, and fibrocytes)
and soluble mediators (cytokines and chemokines) involved in pulmonary fibrosis, pointing …

… CXC chemokine known as a potent neutrophil recruiter. The chemotactic role of CXCL6
requires interaction with the CXC … precise role of these cells in experimental pulmonary fibrosis …

… and chemokine levels in … pulmonary parenchyma [21]. In addition, IFN-γ enhanced Fas/FasL-mediated
apoptosis of alveolar epithelial cells, which play a key role in pulmonary fibrosis […

Background Idiopathic pulmonary fibrosis (IPF) is associated with aberrant expression of
developmental pathways, including Hedgehog (Hh). As Hh signalling contributes to multiple pro…

… inflammation and poor prognosis in pulmonary fibrosis and can be used to assess disease
progression and severity. For instance, IL-8 (a member of the CXC chemokine family) level in …