… adipokine made by subcutaneous adipose tissue, metreleptin (recombinant human methionyl
leptin) is a pillar of therapy in non–HIV-associated lipodystrophy… in lipodystrophy, including …

… lipodystrophy leading to increased risk of diabetes and cardiovascular diseases. With a
shifted trajectory of HIV/AIDS … for the management of HIV-associated lipodystrophy. Several …

… secreted in sEV and function as adipokines (13), could provide a novel mechanism for
altered adipose function and related metabolic abnormalities in HIV lipodystrophy. Interestingly, …

… Lipodystrophy syndromes (LS) constitute a group of rare diseases of the adipose tissue, …
Because of a common pathophysiology involving decreased concentration of the adipokine …

… including lipodystrophy and obesity are prevalent in the setting of treated and untreated HIV
… Imbalance in the production of adipokines (adiponectin and leptin) and infiltration of immune …

… the adipokines AFABP and EFABP in patients with non-HIV LD. … patients with HIV-associated
LD as compared to non-LD HIV-… comprising 132 HIV-infected patients with LD and 150 HIV-…

… HIV-infected patients with lipodystrophy demonstrated a higher index of total lipolysis
compared HIV… metabolism-related gene expression, and release of adipokines and cytokines at …

… , altered adipokine secretion and … function in fat from HIV patients, including inhibited
expression of POLG1 which was suggested as one of key factors in NRTI-induced lipoatrophy [8]. …

… HIV-associated lipodystrophy may be related to accelerated ageing elicited by antiretroviral
drugs and HIV … component in HIV lipodystrophy, we herein compared alterations in …

… In India, the prevalence of lipodystrophy (LD) varies from 22 to 60.7% (8, 9). LD is a problem
… a vital role in lipid and glucose metabolism and release various lipokines and adipokines to …