… cytokines and adipokines 5 5. Giralt M, Domingo P, Villarroya F. Adipose tissue biology and
… the clinical impact of lipodystrophy, reducing diseases related to AIDS and mortality 31 31. …

… (lipodystrophy), including fat wasting (lipoatrophy), within HIV + … Such lipodystrophy is
linked to mitochondrial perturbation … of adipokine expression and mitochondrial toxicity in HIV …

… release from adipocytes of adipokines, such as adiponectin … IR in individuals with HIV-induced
lipodystrophy by acting as … this study suggest that HIV-induced lipodystrophy confers an …

… Of note, in LMNA-linked lipodystrophy, interscapular fat pads display fibrotic changes but
no evidence of ongoing inflammatory processes, suggesting that fibrosis and inflammation are …

… untreated HIV infection, 3,4 the development of clinical lipodystrophy (peripheral lipoatrophy,
… Lipodystrophy was first attributed to HIV PIs; 7 however, subsequent studies demonstrated …

… Leptin is an adipokine that is secreted by adipocytes and … Adiponectin is a major adipokine
that promotes insulin … in patients with HAART‑related lipodystrophy and metabolic syndrome (…

… lipoatrophy with either central lipoatrophy or fat accumulation and, in some patients, fat
accumulation at the neck level, called buffalo-hump. Due to replacement of the more adipose …

… with generalized lipodystrophy or a limited capacity to expand in partial lipodystrophy. …
of buffering postprandial lipids and secreting substantial adipokines, which in turn results in …

… a role in the hypertriglyceridemia of lipodystrophy independent of leptin deficiency and
replacement. Lipodystrophy is … Patients with lipodystrophy have deficiency of adipokines such as …

… associated with lipodystrophy (32). Altered production of other adipokines by lipodystrophic
… described in several studies, mostly related to HIV-related forms of lipodystrophy (4). It could …