Lipodystrophies—disorders of the fatty tissue

B Knebel, D Müller-Wieland, J Kotzka - International Journal of Molecular …, 2020 - mdpi.com
HIV patients with lipodystrophy have a normal immune status, a suppressed HIV viral load
and no AIDS-… concentrations of the metabolic regulatory adipokines leptin and adiponectin. …

Metabolic disorders in Patients with HIV

F Radu, RE Jipa, E Rusu, R Cursaru… - Romanian Journal of …, 2016 - rjdnmd.org
… with subjects without lipodystrophy, HIV patients with lipodystrophy achieve lower insulin-…
hepatic adipokines, known to be part of the pathogenesis of type 2 diabetes [18]. In HIV patients…

Pioglitazone therapy for HIV/HAART-associated lipodystrophy syndrome could increase subcutaneous fat mass in non-lipoatrophic but not in lipoatrophic regions

S Okada, M Konishi, H Ishii - Case Reports, 2016 - casereports.bmj.com
… associated with multiple metabolic disorders, including lipodystrophy, dyslipidaemia and
insulin resistance. HIV/HAART-associated lipodystrophy syndrome (HALS) is characterised by …

[HTML][HTML] New insights into the effects of irisin levels in HIV-infected subjects: correlation with adiposity, fat-free mass, and strength parameters

JCS Trombeta, J Prestes, DC Nascimento… - … of Endocrinology and …, 2017 - SciELO Brasil
… FNDC5/irisin is not only a myokine but also an adipokine. PLoS One. 2013;8(4):e60563.). …
Lipodystrophy associated with highly active anti-retroviral therapy for HIV infection: the …

Prolonged antiretroviral treatment induces adipose tissue remodelling associated with mild inflammation in SIV-infected macaques

A Mausoléo, A Olivo, D Desjardins, A Sáez-Cirión… - Cells, 2022 - mdpi.com
role in controlling HIV infection, these drugs have metabolic side effects [50]. Almost all ARVs
are associated with changes in AT, such as weight gain, lipodystrophy, and … of adipokine

[HTML][HTML] Human immunodeficiency virus infection and the endocrine system

D Zaid, Y Greenman - Endocrinology and Metabolism, 2019 - ncbi.nlm.nih.gov
… a role [ 8 ]. Reduced GH levels are inversely correlated with visceral obesity in HIV lipodystrophy,
as also seen in non-HIV–… by changes in several adipokines. Adiponectin levels are low, …

Visceral adipose tissue and carotid intima-media thickness in HIV-infected patients undergoing cART: a prospective cohort study

MT Beires, A Silva-Pinto, AC Santos… - BMC Infectious …, 2018 - Springer
… that HIV-infected patients under cART with lipodystrophy defined by FMR had a significantly
higher cIMT than those without lipodystrophy, … The purpose of this study was to evaluate the …

Spectrum of disease associated with partial lipodystrophy: lessons from a trial cohort

N Ajluni, R Meral, AH Neidert, GF Brady… - Clinical …, 2017 - Wiley Online Library
… These findings suggest that the development of hypertriglyceridaemia may be related to
absence of peripheral fat depots (and possibly related to changes in their adipokines), but also …

Metabolic syndrome and obesity are the cornerstones of liver fibrosis in HIV-monoinfected patients

M Lemoine, K Lacombe, JP Bastard, M Sébire… - Aids, 2017 - journals.lww.com
… infection for a median duration of 17 years, a phenotype of lipodystrophy was also … levels
of adipokines or sCD14 and sCD163 and the degree of fibrosis in HIV monoinfected patients …

[HTML][HTML] Diabetes in people living with HIV

S Sarkar, TT Brown - Endotext [internet], 2023 - ncbi.nlm.nih.gov
… In a cross-sectional study, HIV+ men with lipodystrophy had a greater insulin resistance
than men without lipodystrophy (21). Lipodystrophy has also been associated with incident …