Lectin complement pathway activation is associated with massive proteinuria in PLA2R-positive membranous nephropathy: a retrospective study

J Li, J Zhang, X Wang, X Zheng, H Gao… - International Journal of …, 2023 - Taylor & Francis
… explored lectin complement pathway activation in PLA2R-associated membranous
nephropathy (MN). … This study explored lectin complement pathway activation in PLA2R-associated …

… alternative pathway is necessary and sufficient for complement activation by anti-THSD7A autoantibodies, which are predominantly IgG4 in membranous nephropathy

P Manral, TN Caza, AJ Storey, LH Beck Jr… - Frontiers in …, 2022 - frontiersin.org
Membranous nephropathy (MN) is an immune kidney disease characterized by glomerular
subepithelial immune complexes (ICs) containing antigen, IgG, and products of complement

Novel biomarkers in membranous nephropathy

Q Liu, J Liu, B Lin, Y Zhang, M Ma, M Yang… - Frontiers in …, 2022 - frontiersin.org
Membranous nephropathy (MN) is the major cause of adult … of primary glomerulonephritis
and end-stage renal disease (ESRD). … Therefore, membrane nephropathy may be improved by …

… lectin, anti-phospholipase A2 receptor antibody and renal outcomes in idiopathic membranous nephropathy and atypical membranous nephropathy: a single center …

Y Zhao, M Cai, Z Jiang, B Dong, Y Yan, Y Wang… - Renal Failure, 2022 - Taylor & Francis
nephropathy [Citation3,Citation4]. It is controversial whether this is a new type of membranous
nephropathy or an early form of secondary membranous nephropathy. From 2006 to 2015…

[HTML][HTML] Novel treatments paradigms: membranous nephropathy

JE Rojas-Rivera, A Ortiz, FC Fervenza - Kidney international reports, 2023 - Elsevier
… Current approach to membranous nephropathy therapy and role of anti-PLA2R in monitoring
disease (2a). Therapeutic algorithm designed, adapted, and modified from figures 30 and …

Novel biomarkers and pathophysiology of membranous nephropathy: PLA2R and beyond

C Murtas, M Bruschi, S Spinelli, X Kajana… - Clinical Kidney …, 2024 - academic.oup.com
… Research on membranous nephropathy truly exploded in the last 15 years. This happened
because of the application of new techniques (laser capture microdissection, mass …

… the lysosome-dependent autophagic pathway contributes to complement membrane attack complex-induced podocyte injury in idiopathic membranous nephropathy

WJ Liu, Z Li, X Chen, X Zhao, Z Zhong, C Yang… - Scientific Reports, 2017 - nature.com
… the frequency of idiopathic membranous nephropathy (IMN), which might ultimately predominate
over IgA nephropathy to become the leading type of primary glomerulopathy in the near …

How times have changed! A cornucopia of antigens for membranous nephropathy

TN Caza, LF Al-Rabadi, LH Beck Jr - Frontiers in Immunology, 2021 - frontiersin.org
… histopathologic features of membranous nephropathy. (A) … ‘primary’ membranous nephropathy.
This will be followed by antigens commonly encountered in membranous lupus nephritis, …

Membranous nephropathy in the kidney allograft

EJ Filippone, JL Farber - Clinical transplantation, 2016 - Wiley Online Library
Membranous nephropathy (MN) may occur in a kidney transplant as recurrence of the
original disease (rMN) or as a de novo MN (dnMN). rMN often occurs early, within the first year, …

Complement regulation and kidney diseases: recent knowledge of the double-edged roles of complement activation in nephrology

M Mizuno, Y Suzuki, Y Ito - Clinical and Experimental Nephrology, 2018 - Springer
… the complement activation and regulation systems, their physiological effects and roles in
maintenance of homeostasis in the host, and how dysregulation of the complement system …