Gap junction intercellular communication in the carcinogenesis hallmarks: is this a phenomenon or epiphenomenon?

R Zefferino, C Piccoli, S Di Gioia, N Capitanio… - Cells, 2019 - mdpi.com
… The aim of the present paper is to verify and discuss the role of Cxs, GJs, and GJIC in
cancer hallmarks, pointing on the different involved mechanisms in the context of the multi-step …

Cancer prevention and therapy of two types of gap junctional intercellular communication–deficient “cancer stem cell”

JE Trosko - Cancers, 2019 - mdpi.com
… On the other hand, cancer cells are characterized by their … cancer cells, that gap junctional
intercellular communication … that might be found with all cancer cells, or to identify the stage …

The role of gap junctions in inflammatory and neoplastic disorders

P Wong, V Laxton, S Srivastava… - International …, 2017 - spandidos-publications.com
Gap junctions are intercellular channels that mediate both … Gap junction intercellular
communication (GJIC) is essential … of gap junction modulators in inflammatory and neoplastic

Facets of communication: gap junction ultrastructure and function in cancer stem cells and tumor cells

A Beckmann, N Hainz, T Tschernig, C Meier - Cancers, 2019 - mdpi.com
… of gap junction channels are crucial for their function in intercellular communication, one …
is to outline the data on gap junction plaque morphology available for cancer cells. Electron …

Gap junctions and cancer: communicating for 50 years

T Aasen, M Mesnil, CC Naus, PD Lampe… - … Reviews Cancer, 2016 - nature.com
… to as tumour promoters were shown to be effective inhibitors of gap junctional intercellular
communication (… For instance, the potent tumour promoter TPA caused a rapid and significant …

Effect of gap junction-mediated intercellular communication on TGF-β induced epithelial-to-mesenchymal transition

S Fukuda, M Akiyama, H Harada… - … research communications, 2019 - Elsevier
… the effect of gap junctional intercellular communication (GJIC) on … role of GJIC in cancer
progression and metastasis and identify potential therapeutic targets for the treatment of cancer

Influence of gap junction intercellular communication composed of connexin 43 on the antineoplastic effect of adriamycin in breast cancer cells

G Jiang, S Dong, M Yu, X Han, C Zheng… - Oncology …, 2017 - spandidos-publications.com
… RA (10 µM) increased gap junction intercellular communication in the two cell types
analyzed. (B) Histograms show the quantitation of dye coupling. N=4; Bars are means ± SD. **…

Gap junction as an intercellular glue: emerging roles in cancer EMT and metastasis

XY Mao, QQ Li, YF Gao, HH Zhou, ZQ Liu, WL Jin - Cancer letters, 2016 - Elsevier
intercellular gap junction is proposed to exacerbate cancer EMT and metastasis Gap junctions
… The gap junctional intercellular communications (GJICs) are formed by the docking of two …

Possible mechanisms of mercury toxicity and cancer promotion: involvement of gap junction intercellular communications and inflammatory cytokines

R Zefferino, C Piccoli, N Ricciardi… - Oxidative medicine …, 2017 - Wiley Online Library
… The mechanisms controlling non gap junction-mediated intercellular communication are, …
Deregulation of gap junctional intercellular communication is a common phenotype of cancer

[HTML][HTML] … fibroblasts accelerate malignant progression of non-small cell lung cancer via connexin 43-formed unidirectional gap junctional intercellular communication

M Luo, Y Luo, N Mao, G Huang, C Teng… - Cellular Physiology and …, 2018 - karger.com
… Background/Aims: Gap junctions, which are … gap junctional intercellular communication
(GJIC) as well as metabolic coupling between neighboring cells. Here, we investigated the role