The role of mifepristone on first trimester miscarriage treatment–A double-blind randomized controlled trial–MiFirsT

B Bettencourt-Silva, MT Rego, C Miranda… - European Journal of …, 2023 - Elsevier
Objectives To evaluate the efficacy of combined mifepristone and misoprostol compared to
misoprostol alone in outpatient medical treatment of first trimester miscarriage. Additionally,
the study intends to compare the rate of complications, adverse effects, and treatment
acceptability between groups. Study Design Single-center double-blind randomized
placebo-controlled trial including women with diagnosis of missed first trimester miscarriage
up to 9 weeks of gestation. Results Between April 2019 and November 2021, 216 women …
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