TCRα-TCRβ pairing controls recognition of CD1d and directs the development of adipose NKT cells
… between the TCR and major histocompatibility complex (MHC). … region, on the other hand,
was permissive to CD1d binding … changes in activation via a superantigen, which raised the …
was permissive to CD1d binding … changes in activation via a superantigen, which raised the …
Determining the immunological characteristics of a novel human monoclonal antibody developed against staphylococcal enterotoxin B
Y Liu, Z Song, S Ge, J Zhang, L Xu, F Yang… - Human Vaccines & …, 2020 - Taylor & Francis
… Citation2 Acting as a superantigen, it binds to class II molecules of the major histocompatibility
complex (MHC II… of Jinan Military Region and were isolated and identified their enterotoxin …
complex (MHC II… of Jinan Military Region and were isolated and identified their enterotoxin …
[HTML][HTML] T-Cell receptor variable β domains rigidify during affinity maturation
… variable β chains binding to the superantigen staphylococcal … 2 loops show interactions with
the major histocompatibility … -H3 loop ensemble upon antigen binding in solution 12,22 was …
the major histocompatibility … -H3 loop ensemble upon antigen binding in solution 12,22 was …
AT Cell ReceptorVe~ Domain Expressed in Bacteria: Does It Dimerize in Solution?
D Plaksin, S Chacko, PMPA Bax, EA Padlan… - ncbi.nlm.nih.gov
… (RGPGRAFVTI) bound to the murine major histocompatibility complex (MHC) class I molecule,
H-… structure of a human class II histocompatibility molecule complexed with superantigen. …
H-… structure of a human class II histocompatibility molecule complexed with superantigen. …
Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer
P Wei, KR Jordan, JD Buhrman, J Lei… - Proceedings of the …, 2021 - National Acad Sciences
… structural studies herein show that the modification of the self-TAA resulted in a subtle change
in the major histocompatibility complex I–TAA structure. … and the extracellular domains of L …
in the major histocompatibility complex I–TAA structure. … and the extracellular domains of L …
Multifunctional chaperone and quality control complexes in adaptive immunity
S Trowitzsch, R Tampé - Annual review of biophysics, 2020 - annualreviews.org
… the maturation of major histocompatibility complex class I (MHC I) proteins, … binds the retrieval
motif, whereas in the neutral pH of the ER lumen, cargo is released (16). Crystal structures …
motif, whereas in the neutral pH of the ER lumen, cargo is released (16). Crystal structures …
Novel insights into the immune response to bacterial T cell superantigens
… terminal oligosaccharide binding (OB)-fold and a carboxy-terminal β-grasp motif, … binding
motif for a zinc atom (shown in purple) that is important for engaging the β-chain of MHC class II…
motif for a zinc atom (shown in purple) that is important for engaging the β-chain of MHC class II…
Nasopharyngeal infection by Streptococcus pyogenes requires superantigen-responsive Vβ-specific T cells
JJ Zeppa, KJ Kasper, I Mohorovic… - Proceedings of the …, 2017 - National Acad Sciences
… of major histocompatibility class II molecules and T-cell receptor (TCR) β-chain variable
domains (… C57BL/6 mice expressing human major histocompatibility complex II molecules (HLA-…
domains (… C57BL/6 mice expressing human major histocompatibility complex II molecules (HLA-…
Development of sandwich chemiluminescent immunoassay based on an anti-staphylococcal enterotoxin B Nanobody–Alkaline phosphatase fusion protein for …
T Sun, Z Zhao, W Liu, Z Xu, H He, B Ning, Y Jiang… - Analytica chimica …, 2020 - Elsevier
… region 3 (CDR3) of Nb37 embedded itself in the opening generated by the major
histocompatibility complex … SO 4 ), and the optical density (OD) of the solution was measured at …
histocompatibility complex … SO 4 ), and the optical density (OD) of the solution was measured at …
T Cell Receptor-Based Therapy in Autoimmune Diseases
T Ramanujam, WV Williams - Biological Approaches to Rational …, 2022 - taylorfrancis.com
… in conjunction with a major histocompatibility complex (MHC) … Whereas the antibodies could
bind an antigen in solution, T cells … region of TCR ~ chains; that of superantigen recognition. …
bind an antigen in solution, T cells … region of TCR ~ chains; that of superantigen recognition. …