… Persistent methicillin-resistant Staphylococcus aureus (MRSA) endovascular infections …
biosynthetic pathways and stringent response mechanism(s) related to this life-threatening …

… The first reports of S. aureus survival within phagocytes was over 60 years ago in the 1950s
which described the intracellular presence and replication of the bacteria within rabbit and …

… extracellular pathogen, accumulating evidence suggests that S. aureus is not only capable
of inducing phagocyte lysis but also able to survive within professional phagocytes, such as …

… Produced antibodies are helpful in the opsonization of bacteria and their engulfment by
phagocytic cells, such as neutrophils and macrophages. CD4 T cells function mainly as helper …

… Of note, PSMs are – except possibly for LukAB/GH – the only leukocyte toxins that are
believed to exert their main function after phagocytosis, and they have been shown to facilitate …

… triggering persister formation in S. aureus, in which neither the stringent response nor the
TA … using phagocytic mammalian THP-1 macrophage-like cells. The viability of the intra-cellular …

… Binding of IgG Fc domain by secreted protein A (SpA) and staphylococcal
immunoglobulin-binding protein (Sbi) protects Staphylococcus aureus from phagocytosis and …

… pathogen, S. aureus since has been shown to survive phagocytosis by neutrophils and
macrophages and even was shown to be internalized by a variety of otherwise non-phagocytic …

… Staphylococcus aureus bacteria are able to grow in a … aureus may also be evading the
host response by invading host cells, including professional and non-professional phagocytes …

… of cell stasis due to the stringent response and increase of polyP compounds 4,5,6 .
Persister cells can form upon induction of a SOS response due to an inhibition of DNA repair by …