Neurogenetic dissection of the Drosophila lateral horn reveals major outputs, diverse behavioural functions, and interactions with the mushroom body

MJ Dolan, S Frechter, AS Bates, C Dan, P Huoviala… - Elife, 2019 - elifesciences.org
… Animals exhibit innate behaviours to a variety of sensory stimuli including olfactory cues. In
… ), is implicated in innate behaviour. However, our structural and functional understanding of …

[图书][B] On aggression

K Lorenz - 2021 - taylorfrancis.com
innate nature of aggressive behaviour and of its driving forces, which must be recognised in
order to determine how best to control the behaviour. … , the only structural basis of which is …

Structural basis for the regulation of human 5, 10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition

DS Froese, J Kopec, E Rembeza, GA Bezerra… - Nature …, 2018 - nature.com
… Severe MTHFR deficiency (MIM #607093) is inherited in an autosomal recessive manner
and is the most common inborn error of folate deficiency 1 with ~200 patients known 2 . To date…

Hypothalamic CRH neurons orchestrate complex behaviours after stress

T Füzesi, N Daviu, JI Wamsteeker Cusulin… - Nature …, 2016 - nature.com
… New insights gained from approaches that establish causal links between innate behaviour
and neural circuits are an important step in furthering our understanding of how the brain …

Structural basis for ubiquitylation by HOIL-1

Q Wu, MG Koliopoulos, K Rittinger… - Frontiers in Molecular …, 2023 - frontiersin.org
… Furthermore, we describe the crystal structure of a C-terminal tandem domain construct of
HOIL-1 comprising the IBR and RING2 domains. Interestingly, the structure reveals a unique bi…

Structural basis of development of multi-epitope vaccine against Middle East respiratory syndrome using in silico approach

S Srivastava, M Kamthania, S Singh… - Infection and drug …, 2018 - Taylor & Francis
… Citation13 PL(pro) facilitate infection by their proteolytic, deubiquitinating, and deISGylating
activities suppressing innate immune response from the host cell. Protein ORF1a (4RSP), a …

Surviving threats: neural circuit and computational implications of a new taxonomy of defensive behaviour

J LeDoux, ND Daw - Nature Reviews Neuroscience, 2018 - nature.com
… Defensive fixed reaction patterns. Similar to reflexes, fixed reaction patterns are more or
less innate behavioural responses that are automatically elicited by particular stimuli and are …

Biological motion as an innate perceptual mechanism driving social affiliation

J Larsch, H Baier - Current Biology, 2018 - cell.com
… Our results reveal individual-level, innate perceptual rules of engagement in mutual
affiliation and provide experimental access to the neural mechanisms of social recognition. …

The innate alarm system in PTSD: conscious and subconscious processing of threat

RA Lanius, D Rabellino, JE Boyd, S Harricharan… - Current opinion in …, 2017 - Elsevier
… and behavioural paradigms aimed specifically at identifying the neurocircuitry and associated
patterns of behaviour involved in subconscious threat processing in PTSD (see Figure 1). …

An innate brainstem self-other system involving orienting, affective responding, and polyvalent relational seeking: Some clinical implications for a “Deep Brain …

FM Corrigan, J Christie-Sands - Medical Hypotheses, 2020 - Elsevier
… the PAG, can lay down deep patterns of emotional and energetic responses to … patterns
and also the residual shock and horror of traumatic experiences. We suggest that the innate