Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant wobbler mice, a model of motor neuron degeneration
… -treated wobbler mice. Astrocytes have been implicated as key cell types in modulating
neurodegeneration … To assess the role of astrocytes in neurodegeneration of wobbler mice, we …
neurodegeneration … To assess the role of astrocytes in neurodegeneration of wobbler mice, we …
Early Signs of Neuroinflammation in the postnatal wobbler mouse model of amyotrophic lateral sclerosis
M Meyer, A Lima, MCG Deniselle… - Cellular and Molecular …, 2023 - Springer
… a reactive response to neurodegeneration, although other … Wobbler mouse model of sALS
provides important information regarding the role of different cells in this disease. Wobblers …
provides important information regarding the role of different cells in this disease. Wobblers …
Neuroprotective effects of testosterone in male wobbler mouse, a model of amyotrophic lateral sclerosis
A Lara, I Esperante, M Meyer, P Liere… - Molecular …, 2021 - Springer
… role of testosterone in neurodegeneration of the Wobbler mouse. Wobblers bear a spontaneous
… Wobbler mice show a spontaneous mutation of the gene that encodes for the Vps 54 …
… Wobbler mice show a spontaneous mutation of the gene that encodes for the Vps 54 …
Little helpers or mean rogue—role of microglia in animal models of amyotrophic lateral sclerosis
H Cihankaya, C Theiss, V Matschke - International journal of molecular …, 2021 - mdpi.com
… M2-type cytokines in wobbler mice. However, the histological and neurological outcomes
of wobbler mice bring to mind the fact that neurodegenerative cytokines released by microglia …
of wobbler mice bring to mind the fact that neurodegenerative cytokines released by microglia …
Steroid profiling in male Wobbler mouse, a model of amyotrophic lateral sclerosis
MC Gonzalez Deniselle, P Liere, A Pianos… - …, 2016 - academic.oup.com
… during neurodegenerative diseases (4, 19). Thus, the neuroprotective effects of PROG have
been shown in models of injured nervous system and in some neurodegenerative diseases (…
been shown in models of injured nervous system and in some neurodegenerative diseases (…
Excitatory-inhibitory imbalance in the brain of the wobbler mouse model of amyotrophic lateral sclerosis substantiated by riluzole and diazepam
SR Andreasen, CJ Lundbye, TB Christensen… - Neuroscience …, 2017 - Elsevier
… ) is a devastating neurodegenerative disease affecting upper … that it may contribute to the
neurodegeneration in familial ALS [39… The wobbler mouse model of ALS displays several of the …
neurodegeneration in familial ALS [39… The wobbler mouse model of ALS displays several of the …
[HTML][HTML] Dysregulated expression and distribution of Kif5α in neurites of wobbler motor neurons
K Kürten, AC Gude, ASC Epplen, J Stein… - Neural regeneration …, 2023 - journals.lww.com
… mice and ALS patients, leading to neurodegeneration. A recent study on a Charcot Marie
Tooth model revealed that compensation for the loss of Kif5α dependent cargo inhibited axonal …
Tooth model revealed that compensation for the loss of Kif5α dependent cargo inhibited axonal …
ROS scavengers decrease γH2ax spots in motor neuronal nuclei of ALS model mice in vitro
M Junghans, F John, H Cihankaya… - Frontiers in Cellular …, 2022 - frontiersin.org
… ) is an incurable neurodegenerative disease characterized by the … breaks (DSBs) in the ALS
model of the Wobbler mouse. … phenotype of the homozygous Wobbler mouse shows a head …
model of the Wobbler mouse. … phenotype of the homozygous Wobbler mouse shows a head …
MicroRNA expression in animal models of amyotrophic lateral sclerosis and potential therapeutic approaches
B Martinez, PV Peplow - Neural regeneration research, 2022 - journals.lww.com
… The wobbler mouse model The wobbler mouse was the first proposed mouse model of
ALS … gray matter of the ventral horn, the site of neurodegeneration. The number of miR-9-positive …
ALS … gray matter of the ventral horn, the site of neurodegeneration. The number of miR-9-positive …
Elevated NLRP3 Inflammasome Activation Is Associated with Motor Neuron Degeneration in ALS
… ) is a fatal neurodegenerative disease characterized by motor … interplay of inflammation and
neurodegeneration in ALS. This … Since the wobbler mouse shows motor neuron degeneration…
neurodegeneration in ALS. This … Since the wobbler mouse shows motor neuron degeneration…