[HTML][HTML] Efficacy of 3-day low dose quinine plus clindamycin versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in …

CO Obonyo, EA Juma, VO Were, BR Ogutu - Malaria Journal, 2022 - Springer
… courses have been associated with a lower treatment efficacy … In our study, the combination
of quinine with clindamycin was … low efficacy observed on the quinine plus clindamycin arm …

Quinine plus clindamycin vs artemether-lumefantrine for treatment of uncomplicated falciparum malaria in western Kenya

CO Obonyo, BR Ogutu - Malaria Journal, 2022 - Springer
… role of clindamycin-based combinations in the treatment of … outcome measures to assess
treatment efficacy. Our results … comparability of treatments (by using oral 12-hourly treatment for …

Efficacy of Quinine Plus Clindamycin Versus Artemether-Lumefantrine For The Treatment of Uncomplicated Plasmodium Falciparum Malaria In Kenyan Children …

C Obonyo, EA Juma, VO Were, BR Ogutu - 2021 - researchsquare.com
… In our study, the combination of quinine with clindamycin was well tolerated and had a
comparable … Children treated using quinine plus clindamycin were more likely to develop severe …

[HTML][HTML] … and safety of re-treatment with the same artemisinin-based combination treatment (ACT) compared with an alternative ACT and quinine plus clindamycin after …

HM Mavoko, C Nabasumba, RI da Luz… - The Lancet Global …, 2017 - thelancet.com
… the efficacy of quinine as a treatment for uncomplicated malaria in DR Congo. … effectiveness
and tolerability of quinine, the reduced availability of the paediatric formulation of clindamycin

[HTML][HTML] … of artesunate-amodiaquine, artemether-lumefantrine and quinine plus clindamycin in the treatment of uncomplicated Plasmodium falciparum malaria in …

Y Lula Ntamba, H Muhindo Mavoko, M Kalabuanga… - PLoS …, 2019 - journals.plos.org
combination treatment (ACT) compared with an alternative ACT and quinine plus clindamycin
… The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for …

Should we abandon quinine plus antibiotic for treating uncomplicated falciparum malaria? A systematic review and meta-analysis of randomized controlled trials

T Song, J Chen, L Huang, W Gan, H Yin, J Jiang… - Parasitology …, 2016 - Springer
… all regimens have equivalent treatment effect at the 28th day. … clindamycin is recommended
as a second-line medicine for … This combination could remedy ACT shortfall in some regions…

[HTML][HTML] Clinical pharmacokinetics of quinine and its relationship with treatment outcomes in children, pregnant women, and elderly patients, with uncomplicated and …

T Saeheng, K Na-Bangchang - Malaria Journal, 2022 - Springer
… , and is always used in combination with an additional agent, such as doxycycline [1]. Quinine
is also used, in combination with clindamycin, for uncomplicated Plasmodium falciparum …

[HTML][HTML] Macrolides and associated antibiotics based on similar mechanism of action like lincosamides in malaria

T Gaillard, J Dormoi, M Madamet, B Pradines - Malaria journal, 2016 - Springer
… examined the effects of azithromycin and the lincosamide clindamycin, … clindamycin are
effective and well tolerated in the treatment of uncomplicated malaria in combination with quinine

[HTML][HTML] Systematic literature review and meta-analysis of the efficacy of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in …

M Saito, ME Gilder, F Nosten, R McGready, PJ Guerin - Malaria Journal, 2017 - Springer
… the actual drug combinations and outcome endpoints were … assessing treatment efficacy for
uncomplicated falciparum … of parasitologically confirmed uncomplicated falciparum. Studies …

[HTML][HTML] Drug treatment and prevention of malaria in pregnancy: a critical review of the guidelines

KAJ Al Khaja, RP Sequeira - Malaria journal, 2021 - Springer
… variables that include therapeutic efficacy of drugs against P. … quinine monotherapy to treat
uncomplicated malaria during first trimester, instead of quinine plus clindamycin combination