Safety and efficacy of intra-articular anti-tumor necrosis factor α agents compared to corticosteroids in a treat-to-target strategy in patients with inflammatory arthritis …

…, L Zugaro, P Cipriani, A Conchiglia… - International …, 2016 - journals.sagepub.com
anti-TNFα treatment offers considerable improvement in systemic inflammatory joint diseases,
many … Application of MRI sequences and use of intravenous injection of gadolinium-DTPA (…

[HTML][HTML] Novel pharmacological therapy in inflammatory bowel diseases: beyond anti-tumor necrosis factor

C Pagnini, TT Pizarro, F Cominelli - Frontiers in Pharmacology, 2019 - frontiersin.org
… confirms the important therapeutic effect of blocking leukocyte … -treatment with steroids,
and/or a supplementary infusion at … with risankizumab (200 mg IV and 600 mg IV) showed a …

Efficacy and safety profile of antitumor necrosis factor-α versus anti-integrin agents for the treatment of Crohn's disease: a network meta-analysis of indirect …

…, K Papamichael, NV Casteele, GJ Mantzaris, A Gils… - … therapeutics, 2016 - Elsevier
… AEs of anti-integrins, including infusion reactions and … summary treatment effects were
estimated using the random-effects … biologics are presented in Table IV. Similarly, no statistically …

Anticancer therapy with TNF α and IFN γ: A comprehensive review

J Shen, Z Xiao, Q Zhao, M Li, X Wu, L Zhang… - Cell …, 2018 - Wiley Online Library
… But the tumour-targeting and therapeutic effects have variable … malignancy IV 0.1, 0.5, or 1.0
mg/m 2 /d Six-hour IV infusionsTumour necrosis factor alpha and IFNγ are now affirmed as …

Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury

A Proudfoot, A Bayliffe, CM O'Kane, T Wright, A Serone… - Thorax, 2018 - thorax.bmj.com
… permission to reuse the content in many different ways. … risk of mild infusion reactions
following intravenous dosing.31 … , a similar GSK1995057 treatment effect was not apparent in …

Update on anti-tumor necrosis factor agents and other new drugs for inflammatory bowel disease

BL Cohen, DB Sachar - Bmj, 2017 - bmj.com
… of many newer biologic therapies, showed a treatment burden of … Yet anti-TNF therapy, most
often intravenous infliximab or … at risk of infusion reactions and treatment failure.Because the …

Efficacy, safety and pharmacokinetics of biosimilars of anti-tumor necrosis factor-α agents in rheumatic diseases; A systematic review and meta-analysis

…, P Kudaravalli, D Micic, A Ido, A Sakuraba - Journal of …, 2017 - Elsevier
treatment of immune mediated diseases including rheumatoid arthritis (RA), ankylosing
spondylitis (AS), and psoriasis [1]. Many biological therapies … 2 h IV infusion MTX 6–16 mg/week …

The effectiveness of the anti-tumor necrosis factor therapy infliximab in neuro-Behçet's disease: a systematic review and meta-analysis

RHA Mohammed… - Journal of International …, 2023 - journals.sagepub.com
Treatment effect size was determined by a random effects … The study focused on the effect
of infliximab on more than oneIntravenous infusion of infliximab was added to MTX (10–…

Anti-tumour necrosis factor-alpha agent therapy, compared with conventional therapy, reduces the relapse of uveitis in patients with Behçet's disease: a systematic …

X Zhou, X Shi, Y Ren, T Yan, Q Ye - Frontiers in Pharmacology, 2022 - frontiersin.org
efficacy and safety of anti-TNF-α therapy and summarize the efficacy of anti-TNF-α therapy
… the status of anti-TNF-α therapy among the multiple available therapeutic options. Based on …

Tissue drug concentrations of anti-tumor necrosis factor agents are associated with the long-term outcome of patients with Crohn's disease

T Yoshihara, S Shinzaki, S Kawai, H Fujii… - Inflammatory bowel …, 2017 - academic.oup.com
Many reports indicate that a high-serum trough level of anti-… of CD, and anti-TNF therapy is
essential for treating patients … a steady loss of efficacy of anti-TNF therapy. To investigate the …