Anti-TNF-α therapies for the treatment of Crohn's disease: the past, present and future
M Berns, DW Hommes - Expert opinion on investigational drugs, 2016 - Taylor & Francis
… the overexpression of tumor necrosis factor α (TNF-α), a … A more practical alternative to
intravenous infusions includes … that contribute to the overall therapeutic effects of the biologics. …
intravenous infusions includes … that contribute to the overall therapeutic effects of the biologics. …
Use of anti-TNF drug levels to optimise patient management
K Papamichael, AS Cheifetz - Frontline gastroenterology, 2016 - fg.bmj.com
… -TNF therapy efficacy, safety and cost. However, … Anti-tumour necrosis factor (TNF)
therapies, infliximab, adalimumab, … consequently treatment failure due to infusion reactions.4 ,5 …
therapies, infliximab, adalimumab, … consequently treatment failure due to infusion reactions.4 ,5 …
Intravenous infusion of human adipose mesenchymal stem cells modifies the host response to lipopolysaccharide in humans: a randomized, single-blind, parallel …
D Perlee, LA van Vught, BP Scicluna, A Maag… - Stem Cells, 2018 - academic.oup.com
… MSCs can exert many different immunomodulatory effects that … Tumor necrosis factor (TNF),
interleukin (IL)-1β, IL-2, IL-4, IL-… use of intravenous infusion of ASCs in the treatment of sepsis …
interleukin (IL)-1β, IL-2, IL-4, IL-… use of intravenous infusion of ASCs in the treatment of sepsis …
… vasculature with TNF leads effector T cells to the tumor and enhances therapeutic efficacy of immune checkpoint blockers in combination with adoptive cell therapy
… several of these antibodies for the treatment of various … of tumor necrosis factor-α (TNF) to
the tumor endothelium with Cys… following day were iv injected into the lateral tail vein with 0.5 × …
the tumor endothelium with Cys… following day were iv injected into the lateral tail vein with 0.5 × …
Tocilizumab for the treatment of Behçet uveitis that failed interferon alpha and anti-tumor necrosis factor-alpha therapy
H Eser Ozturk, M Oray… - Ocular immunology and …, 2018 - Taylor & Francis
… multiple retinal infiltrates in both eyes. The patient was treated with intravenous
methylprednisolone pulse therapy (… resistant to TCZ treatment during the first five infusions and we …
methylprednisolone pulse therapy (… resistant to TCZ treatment during the first five infusions and we …
[PDF][PDF] Anti-tumor necrosis factor therapy is not associated with post-operative infection: results from prospective cohort of ulcerative colitis and Crohn's disease …
BL Cohen, P Fleshner, SV Kane, HH Herfarth… - …, 2019 - academia.edu
… multi-center prospective study to determine if exposure to anti… comparing the efficacy and
safety of two biologic therapies, … ; or 2) placebo IV infusions/active ADA SC injections (160/80/…
safety of two biologic therapies, … ; or 2) placebo IV infusions/active ADA SC injections (160/80/…
Inflammatory bowel disease and targeted oral anti-TNFα therapy
OR Griffiths, J Landon, RE Coxon, K Morris… - Advances in protein …, 2020 - Elsevier
… tumor necrosis factor-alpha (hTNFα) through the use of anti-… generation of ADAs that reduce
treatment efficacy over time. For … therapy would be one that has the effect of intravenous anti-…
treatment efficacy over time. For … therapy would be one that has the effect of intravenous anti-…
Effects of combination therapy with immunomodulators on trough levels and antibodies against tumor necrosis factor antagonists in patients with inflammatory bowel …
Y Qiu, R Mao, B Chen, S Zhang, J Guo, Y He… - Clinical …, 2017 - Elsevier
… Studies investigating the association between clinical efficacy and infusion reactions with
anti-TNF-α … Several observational studies and randomized controlled trials have examined the …
anti-TNF-α … Several observational studies and randomized controlled trials have examined the …
Safety, tolerability and efficacy of repeated intravenous infusions of KHK4083, a fully human anti-OX40 monoclonal antibody, in Japanese patients with moderate to …
H Nakagawa, H Iizuka, O Nemoto, M Shimabe… - Journal of …, 2020 - Elsevier
… OX40, a member of the tumor necrosis factor receptor (TNFR) … to severe AD by assessing
treatment-emergent adverse events (… reactions of mild or moderate severity occurred in several …
treatment-emergent adverse events (… reactions of mild or moderate severity occurred in several …
Association of preoperative anti–tumor necrosis factor therapy with adverse postoperative outcomes in patients undergoing abdominal surgery for ulcerative colitis
AS Kulaylat, AN Kulaylat, EW Schaefer, A Tinsley… - JAMA …, 2017 - jamanetwork.com
… for the treatment of UC in 2005 and was followed several years … to having an effect on
restorative procedures, anti-TNF … requires in-office intravenous infusion, unlike the subcutaneous …
restorative procedures, anti-TNF … requires in-office intravenous infusion, unlike the subcutaneous …