20 years of experience with tumour necrosis factor inhibitors: what have we learned?

R Caporali, G Crepaldi, V Codullo, F Benaglio… - …, 2018 - academic.oup.com
… from their use about therapeutic effects and adverse events. … the ones that require iv antibiotic
therapy and/ or hospitalization… Therapeutic efficacy of multiple intravenous infusions of anti-…

[HTML][HTML] An engineered monovalent anti–TNF-α antibody with pH-sensitive binding abrogates immunogenicity in mice following a single intravenous dose

JM Watkins, JD Watkins - The Journal of Immunology, 2022 - journals.aai.org
… are associated with lower treatment efficacy. The enhanced incidence … Tumor necrosis factor-α
is a pleiotropic, proinflammatory … However, it is immunogenic in many patients, resulting in …

Acute effects of alemtuzumab infusion in patients with active relapsing-remitting MS

K Thomas, J Eisele, FA Rodriguez-Leal… - Neuroimmunology & …, 2016 - AAN Enterprises
therapy, treated for 3 days with 1,000 mg IV … (IFN)–γ, and tumor necrosis factor (TNF)–α
using a commercial multiplexed … 20 The rapid onset of alemtuzumab treatment effects can be …

Osteonecrosis and osteomyelitis of the jaw associated with tumour necrosis factor-alpha (TNF-α) inhibitors: a systematic review

…, V Moraschini, CFAB Mourão, O Akintola, A Lalli - British Journal of Oral …, 2020 - Elsevier
… Initially: given at the clinic or at an infusion centre as an IV at … , is now available in many
countries for use in rheumatoid … of anti TNF-α treatment and the most common TNF-α inhibitor …

Treatment effectiveness and treatment patterns among rheumatoid arthritis patients after switching from a tumor necrosis factor inhibitor to another medication

MMK Bonafede, JR Curtis, D McMorrow… - ClinicoEconomics …, 2016 - Taylor & Francis
… After treatment failure with a tumor necrosis factor inhibitor (TNFi), patients with rheumatoid
… This study compared treatment patterns and treatment effectiveness between TNFi cyclers …

Enhancing anti-tumour efficacy with immunotherapy combinations

F Meric-Bernstam, J Larkin, J Tabernero, C Bonini - The Lancet, 2021 - thelancet.com
… in selecting therapy and developing combination therapies. … approvals in several cancer
types—eg, bladder cancer, non-… GITR=glucocorticoid-induced tumour necrosis factor receptor …

A Study on Safety Profile and Clinical Outcomes of Tumor Necrosis Factor-Alpha Inhibitors in Patients with Ankylosing Spondylitis in a Tertiary Care Centre

E Selvaprakash - 2020 - repository-tnmgrmu.ac.in
… The study drug infliximab was infused intravenously in a … potentially associated with treatment
effectiveness. Some factors … of infusion reactions and the discontinuation of the treatment. …

Serum levels of interleukin-6, interleukin-8, interleukin-10, and tumor necrosis factor-α, renal function biochemical parameters and clinical outcomes in pediatric …

F Gorjipour, Z Totonchi, M Gholampour Dehaki… - …, 2019 - journals.sagepub.com
… via radial and right internal jugular vein, respectively. Heparin, … tried to show the relation of
multiple factors (after operation) … infusions, they are presumably exposed to higher levels of …

Intravenous administration of expanded allogeneic adipose-derived mesenchymal stem cells in refractory rheumatoid arthritis (Cx611): results of a multicentre, dose …

…, R García-Vicuña, L Carreño, A Alonso… - Annals of the …, 2017 - ard.bmj.com
… , such as CD40 (tumour necrosis factor receptor; TNFR), CD80 (… to assess the safety of
intravenous (iv) infusions of eASCs in … treated with Cx611, as treatment effect waned or fluctuated (…

Human intratumoral therapy: Linking drug properties and tumor transport of drugs in clinical trials

A Huang, MM Pressnall, R Lu, SG Huayamares… - Journal of controlled …, 2020 - Elsevier
… The most common route of administration is IV, because most … lymphodepletion treatment
prior to modified T-cell infusion to … can be harnessed to maximize therapeutic effects. …