The 5-HT 2C receptor (R) displays a widespread distribution in the CNS and is involved in
the action of 5-HT in all brain areas. Knowledge of its functional role in the CNS …

… therapeutic use of this class should they reach approval status. Additional avenues include
5-HT2C receptor agonists, … dependence, and may have therapeutic potential. It is anticipated …

… Converging studies provide a demonstration of the therapeutic potential of 5-HT2C receptor
… future therapeutic potential for 5-HT2C receptor agonists in SUD, but further scrutiny of …

… addictive effects. For example, the rate-suppressing effects of both the indirect serotonin
receptor agonist fenfluramine and the 5-HT 2C receptor … in the therapeutic potential of CH. Most …

… prospects 5-HT 2C R ligands as potential therapeutics given its value as a … diseases including
eating disorders, drug addiction, schizophrenia, mood disorders, impulse control disorders…

… strategies for these disorders are ineffective at a population level. Lorcaserin, a 5-HT 2C
receptor agonist, has shown potential at reducing the symptoms of substance use disorder. This …

… 5-HT2CR PAMs may hold therapeutic potential for obesity. … activity to investigate the
therapeutic potential of 5-HT2CR … 2C receptor agonists and their evaluation as potential antipsy…

… 2A receptor agonists and antagonists have been evaluated as potential treatments for addiction.
… interest in their potential to treat a variety of diseases including depression, anxiety, and …

… of 5-HT receptors, including 5-HT2A and 5-HT2C receptors, … receptor subtypes responsible
for their therapeutic potential, … proposed that 5-HT2C receptor agonists may have potential to …

… of 5-HT 2C receptor agonists on a number of behavioral … to therapy with lorcaserin (and
5-HT 2C receptor agonists in general)… other 5-HT 2C receptor agonists relevant to reward-related …