Toll-like receptors as a therapeutic target in cancer, infections and inflammatory diseases
L Flórez-Álvarez, L Ruiz-Perez, N Taborda… - …, 2020 - Future Medicine
… inflammation and inducing the adaptive immune response, these are potential therapeutic
targets … immune response, either to improve the effectiveness of vaccines or control infections. …
targets … immune response, either to improve the effectiveness of vaccines or control infections. …
Targeting toll-like receptors for cancer therapy
MJ Braunstein, J Kucharczyk, S Adams - Targeted oncology, 2018 - Springer
… These factors have complicated the development of TLRs as therapeutic targets, and “targeting”
TLRs for cancer therapy may mean exploiting their function by using agonists (eg as a …
TLRs for cancer therapy may mean exploiting their function by using agonists (eg as a …
[HTML][HTML] Toll-like receptors as a therapeutic target in the era of immunotherapies
… TLRs in infectious diseases, cancers, and autoimmune diseases and therapeutic regimens
… Toll-like receptors are employed as therapeutic targets as well as vaccine adjuvants in viral …
… Toll-like receptors are employed as therapeutic targets as well as vaccine adjuvants in viral …
Toll-like receptors: promising therapeutic targets for inflammatory diseases
… progression of multiple diseases such as cancer, autoimmune, and inflammatory diseases. In
… in the pathogenesis of inflammatory diseases and how targeting of TLRs offers a promising …
… in the pathogenesis of inflammatory diseases and how targeting of TLRs offers a promising …
Recent clinical trends in Toll‐like receptor targeting therapeutics
… and signaling mechanisms of Toll-like receptors. A, A typical … Therapeutics targeting
immune-related diseases mediated … cancers, viral infection, immune diseases, and inflammation. …
immune-related diseases mediated … cancers, viral infection, immune diseases, and inflammation. …
Pathogen recognition and Toll-like receptor targeted therapeutics in innate immune cells
S Tartey, O Takeuchi - International reviews of immunology, 2017 - Taylor & Francis
… immune diseases and cancer. This remarkable ability of TLRs to initiate and … inflammation
makes them attractive therapeutic targets. However, as with many targets for anti-inflammatory …
makes them attractive therapeutic targets. However, as with many targets for anti-inflammatory …
Potential therapeutic targets for inflammation in toll-like receptor 4 (TLR4)-mediated signaling pathways
… therapeutic approach to treat inflammatory diseases. Here we review the therapeutic targets
… in TLR-4 signaling pathways that are critical for suppressing chronic inflammatory disorders. …
… in TLR-4 signaling pathways that are critical for suppressing chronic inflammatory disorders. …
Toll-like receptors in immunity and inflammatory diseases: Past, present, and future
K Vijay - International immunopharmacology, 2018 - Elsevier
… Toll-like receptors (TLRs) are one of these PRRs expressed by various … targeted for
therapeutic drug development for various infectious and inflammatory diseases including cancer. …
therapeutic drug development for various infectious and inflammatory diseases including cancer. …
[HTML][HTML] Inhibition of toll-like receptor signaling as a promising therapy for inflammatory diseases: a journey from molecular to nano therapeutics
W Gao, Y Xiong, Q Li, H Yang - Frontiers in physiology, 2017 - frontiersin.org
… diseases, they have emerged as new therapeutic targets. … risk for inflammatory diseases and
autoimmune disorders, such as … , gastrointestinal inflammation, and even cancer. Evidences …
autoimmune disorders, such as … , gastrointestinal inflammation, and even cancer. Evidences …
[PDF][PDF] Targeting Toll-like receptors against cancer
B Du, QL Jiang, J Cleveland… - Journal of Cancer …, 2016 - pdfs.semanticscholar.org
… Therapeutic targeting of innate immunity with Toll-like … Eritoran suppresses colon cancer
by altering a functional balance in Toll-like receptors that bind lipopolysaccharide. Cancer Res …
by altering a functional balance in Toll-like receptors that bind lipopolysaccharide. Cancer Res …