… of Ii and MHC-II molecules (either individually or as the preformed heterodimer) contribute
to complex formation (Fig. 2B), possibly even initiating complex formation whilst the CLIP and …

… ground-state crystal structures of human MHC class I and class II proteins bound to a …
structures of human MHC complexes in the absence of any other binding partner. In each structure, …

… Three-dimensional plotting and morphological data analysis were performed with the
free software Gwyddion. The histogram of the cell height data was obtained directly from the …

… In human and mouse, MHC-I heavy chains are encoded by thousands of different alleles …
distinct three-dimensional (3D) structure of the MHC-I PBG (31). Each classical MHC-I molecule …

… class I, III and II) in macrophages using 3D-FISH. Since this complex presents major differences
in humans … presence of the centromere between class III and class II regions in pigs, the …

… major histocompatibility complex (MHC) class I, and class II respectively. In addition to the
many steps, several participating proteins, and multiple cellular compartments involved in the …

… TCRs bind class I and class II peptide/MHC complexes, which we … and presented by major
histocompatibility complex (MHC) … from three-dimensional coordinates are shown in Figure 2. …

… the three-dimensional protein structures. As such, summarizing these restraints into possible
modes of interaction would be critical for structural modeling of these complexes. To this …

The repertoire of peptides displayed in vivo by MHC II molecules derives from a wide spectrum
of proteins produced by different cell types. Although intracellular endosomal processing …

… The three-dimensional structure of HLA-B27 at 2.1 A resolution suggests a general … a
peculiar three-dimensional shape that has been preserved on both class I and class II molecules …