Role of membrane environment and membrane-spanning protein regions in assembly and function of the Class II Major Histocompatibility complex
AM Dixon, S Roy - Human Immunology, 2019 - Elsevier
… of Ii and MHC-II molecules (either individually or as the preformed heterodimer) contribute
to complex formation (Fig. 2B), possibly even initiating complex formation whilst the CLIP and …
to complex formation (Fig. 2B), possibly even initiating complex formation whilst the CLIP and …
Major histocompatibility complex (MHC) class I and MHC class II proteins: conformational plasticity in antigen presentation
M Wieczorek, ET Abualrous, J Sticht… - Frontiers in …, 2017 - frontiersin.org
… ground-state crystal structures of human MHC class I and class II proteins bound to a …
structures of human MHC complexes in the absence of any other binding partner. In each structure, …
structures of human MHC complexes in the absence of any other binding partner. In each structure, …
Clustering of major histocompatibility complex-class I molecules in healthy and cancer colon cells revealed from their nanomechanical properties
… Three-dimensional plotting and morphological data analysis were performed with the
free software Gwyddion. The histogram of the cell height data was obtained directly from the …
free software Gwyddion. The histogram of the cell height data was obtained directly from the …
Structural and biochemical analyses of swine major histocompatibility complex class I complexes and prediction of the epitope map of important influenza A virus …
S Fan, Y Wu, S Wang, Z Wang, B Jiang, Y Liu… - Journal of …, 2016 - Am Soc Microbiol
… In human and mouse, MHC-I heavy chains are encoded by thousands of different alleles …
distinct three-dimensional (3D) structure of the MHC-I PBG (31). Each classical MHC-I molecule …
distinct three-dimensional (3D) structure of the MHC-I PBG (31). Each classical MHC-I molecule …
The 3D nuclear conformation of the major histocompatibility complex changes upon cell activation both in porcine and human macrophages
F Mompart, A Kamgoué, Y Lahbib-Mansais… - BMC Molecular and Cell …, 2021 - Springer
… class I, III and II) in macrophages using 3D-FISH. Since this complex presents major differences
in humans … presence of the centromere between class III and class II regions in pigs, the …
in humans … presence of the centromere between class III and class II regions in pigs, the …
[HTML][HTML] A step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cells
S Sadegh-Nasseri - F1000Research, 2016 - ncbi.nlm.nih.gov
… major histocompatibility complex (MHC) class I, and class II respectively. In addition to the
many steps, several participating proteins, and multiple cellular compartments involved in the …
many steps, several participating proteins, and multiple cellular compartments involved in the …
Geometrical characterization of T cell receptor binding modes reveals class‐specific binding to maximize access to antigen
… TCRs bind class I and class II peptide/MHC complexes, which we … and presented by major
histocompatibility complex (MHC) … from three-dimensional coordinates are shown in Figure 2. …
histocompatibility complex (MHC) … from three-dimensional coordinates are shown in Figure 2. …
[HTML][HTML] Extracellular crosslinking mass spectrometry reveals HLA class I–HLA class II interactions on the cell surface
… the three-dimensional protein structures. As such, summarizing these restraints into possible
modes of interaction would be critical for structural modeling of these complexes. To this …
modes of interaction would be critical for structural modeling of these complexes. To this …
The dendritic cell major histocompatibility complex II (MHC II) peptidome derives from a variety of processing pathways and includes peptides with a broad spectrum of …
The repertoire of peptides displayed in vivo by MHC II molecules derives from a wide spectrum
of proteins produced by different cell types. Although intracellular endosomal processing …
of proteins produced by different cell types. Although intracellular endosomal processing …
The major histocompatibility complex
DS Monos, RJ Winchester - Clinical Immunology, 2019 - Elsevier
… The three-dimensional structure of HLA-B27 at 2.1 A resolution suggests a general … a
peculiar three-dimensional shape that has been preserved on both class I and class II molecules …
peculiar three-dimensional shape that has been preserved on both class I and class II molecules …