… state of mixtures science and provide tools for practitioners … with mixtures research, we are
critically evaluating findings in … Disclaimer The views expressed in this chapter are those of …

… a non-toxic environment, we describe and evaluate eco-epidemiological methods that
include methods to diagnose and predict the impacts of chemical mixtures. We start from aquatic …

… computational tools, sometimes referred to as NAMs, to assess … by the chemical stressors,
in a risk assessment. First, a risk … : Requirements, current approaches and future perspectives. …

… to assess how emerging science and new tools can be applied to study multiple stressors at
a … This approach may be useful to predict effects when such mixtures are present in the field. …

… Novel tools could support mixture RA mainly by providing a better understanding of the …
characterisation for mixtures and for cumulative exposure to multiple stressors still need to …

… ecological and ecotoxicological points of view, which poses … assess and manage multiple
stressors—including mixtures of … tools and the introduction of solution-focused assessment …

… Hence, for assessing the risk that chemical mixtures might … We conclude with future
perspectives and research needs for … Here we define biomarkers as a tool to quantitatively …

… environmental risk of chemical and biological stressors at the … in the future assessment of
chemical mixtures and was … perspective to ensure their usefulness for risk assessment. A major …

… stressors over a lifetime. However, even newly developed approaches such as grouping of
… silico tools in hazard assessment and how these streams of evidence can be combined for …

… requires revision of assessment perspectives that focus on … availability of tools for big data
evaluation and pattern analysis … and/or the presence of multiple stressors, eg, in urbanized …