The medial habenula-interpeduncular nucleus pathway in nicotine sensitization: the role of α3β4 nicotinic acetylcholine receptors and substance P

B Eggan, S McCallum - Neuroscience of Nicotine, 2019 - Elsevier
… as an upstream modulator of the mesolimbic reward pathway. … in this pathway and other
receptors such as the substance P … In addition to the cholinergic populations of the IPN, the IPN …

The role of the medial habenula cholinergic system in addiction and emotion-associated behaviors

HW Lee, SH Yang, JY Kim, H Kim - Frontiers in psychiatry, 2019 - frontiersin.org
… neuropeptide substance P and a ventral region containing dense cholinergic neurons. …
In this review, we will discuss how cholinergic signaling in the MHbV–IPN pathway affects …

Opposing effects of an atypical glycinergic and substance P transmission on interpeduncular nucleus plasticity

…, R Von Itter, D Jing, P Koppensteiner… - …, 2019 - nature.com
… Recent studies have shown that a potentiation of either glutamatergic or cholinergic
transmission in the vMHb-CIPN pathway leads to a suppression of fear memory [3, 4]. Consistently, …

Untangling the dorsal diencephalic conduction system: a review of structure and function of the stria medullaris, habenula and fasciculus retroflexus

…, B Lim, M Roman, D Barry, P Tierney… - Brain Structure and …, 2020 - Springer
… dorsal diencephalic conduction system (DDCS) is a highly conserved pathway linking the …
primarily cholinergic, glutamatergic and GABAergic, with primary GABAergic and cholinergic

[HTML][HTML] Understanding the habenula: A major node in circuits regulating emotion and motivation

JL Ables, K Park, I Ibañez–Tallon - Pharmacological research, 2023 - Elsevier
… the habenula's cholinergic and non-cholinergic components in … neurons also demonstrate
medial to lateral topographical … Nicotine and substance P differentially regulate neuronal …

The medial habenula and interpeduncular nucleus circuitry is critical in addiction, anxiety, and mood regulation

I McLaughlin, JA Dani, M De Biasi - Journal of neurochemistry, 2017 - Wiley Online Library
… Furthermore, adaptations in cholinergic components may represent a significant facet of …
topographic organization of the habenulo-interpeduncular pathway: an HRP study in the rat. J. …

The dorsal diencephalic conduction system in reward processing: Spotlight on the anatomy and functions of the habenular complex

M Fakhoury - Behavioural Brain Research, 2018 - Elsevier
substance P-ergic and glutamatergic, and that the ventral-center and lateral part of the MHb
are both cholinergic … Lesion of the habenulo-interpeduncular tract Decreased rate of LH self-…

Acetylcholine potentiates glutamate transmission from the habenula to the interpeduncular nucleus in losers of social conflict

M Kinoshita, H Okamoto - Current Biology, 2023 - cell.com
systems. Previously, we showed that the Hb-interpeduncular nucleus (IPN) pathway controls
… The zebrafish Hb-IPN pathway consists of three parallel pathways: lateral subnucleus of the …

Development and connectivity of the habenular nuclei

S Roberson, ME Halpern - Seminars in cell & developmental biology, 2018 - Elsevier
… new information about the signaling pathways that regulate their … Substance P producing
neurons are found in higher numbers in the left dHb, whereas the vast majority of cholinergic

The Habenulo-Interpeduncular Pathway and Nicotine Withdrawal

CD Fowler - Negative Affective States and Cognitive Impairments in …, 2017 - Elsevier
… of the habenulo-interpeduncular (MHb–IPN) pathway. MHb fibers are cholinergic, glutamatergic,
and/or express substance P and … Substance P and glutamatergic fibers from the dMHb …