Toward automated enzymatic synthesis of oligosaccharides
… such as glycoproteins for functional studies and biomedical applications. One example is
the use of … With a goal of achieving automated synthesis of complex oligosaccharides, many …
the use of … With a goal of achieving automated synthesis of complex oligosaccharides, many …
Automated chemical oligosaccharide synthesis: novel approach to traditional challenges
… oligosaccharide synthesis using traditional manual synthesis … and potentially transformative
automated technologies that … found a broad application in automated synthesis (vide infra). …
automated technologies that … found a broad application in automated synthesis (vide infra). …
Programmable one-pot synthesis of oligosaccharides
… often conjugated with proteins as glycoproteins or with lipids as … glycoproteins or glycolipids
often exist as mixtures, and as a consequence, it is difficult to isolate individual glycoproteins …
often exist as mixtures, and as a consequence, it is difficult to isolate individual glycoproteins …
Strategies for automated enzymatic glycan synthesis (AEGS)
KP Hussnaetter, P Palm, A Pich, M Franzreb… - Biotechnology …, 2023 - Elsevier
Glycans are the most abundant biopolymers on earth and are constituents of glycoproteins,
glycolipids, and proteoglycans with multiple biological functions. The availability of different …
glycolipids, and proteoglycans with multiple biological functions. The availability of different …
Hierarchical and programmable one-pot synthesis of oligosaccharides
… and library available to the research community, the goal of oligosaccharide synthesis may
be realized to facilitate the study of glycans and their roles in glycoproteins and glycolipids. …
be realized to facilitate the study of glycans and their roles in glycoproteins and glycolipids. …
An automated platform for the enzyme-mediated assembly of complex oligosaccharides
… Automated synthesis has made it possible for non-specialists to prepare almost every
possible peptide 1 and oligonucleotide 2 sequence, and the broad availability of the resulting …
possible peptide 1 and oligonucleotide 2 sequence, and the broad availability of the resulting …
Oligosaccharide synthesis and translational innovation
L Krasnova, CH Wong - Journal of the American Chemical Society, 2019 - ACS Publications
… of homogeneous samples except for glycoproteins with multiple glycosylation sites. The …
This strategy is particularly suited for the automated synthesis of oligosaccharides as common …
This strategy is particularly suited for the automated synthesis of oligosaccharides as common …
Automated oligosaccharide synthesis: techniques and applications
M Hurevich, J Kandasamy… - … Synthesis: Strategies …, 2016 - Wiley Online Library
… Carbohydrates mainly exist as glycoproteins and glycolipids (glycoconjugates) on cell … of
the target oligosaccharide at the end of the automated synthesis procedure and demonstrated …
the target oligosaccharide at the end of the automated synthesis procedure and demonstrated …
Machine‐Driven Chemoenzymatic Synthesis of Glycopeptide
… Glycans often express their functions by attaching to proteins (called glycoproteins) or lipids
(… This work will enable an improved instrument for total automation synthesis of glycopeptide …
(… This work will enable an improved instrument for total automation synthesis of glycopeptide …
Chemoenzymatic methods for the synthesis of glycoproteins
C Li, LX Wang - Chemical reviews, 2018 - ACS Publications
… synthesis of oligosaccharides and glycoproteins. … and glycoproteins, especially for those
glycoconjugates containing α-… new tools for oligosaccharide and glycoprotein synthesis. …
glycoconjugates containing α-… new tools for oligosaccharide and glycoprotein synthesis. …