… , inhibitory domain; C-TAD, C-terminal transactivation domain… However, the extent to which
transcription factors including … Thus, it is plausible that a modulation of HIFα action due to …

… HIF-1α and HIF-2α each has two transactivation domains (… co-activators to modulate gene
transcription under hypoxia, while … HIFα has an oxygen-dependent degradation domain (ODDD…

… the up-regulation of HIF-1α transcription when cells had the … the transactivation activity of
HIF-1 is primarily modulated by … the C-terminal transactivation domain (C-TAD) of HIF-1α and …

… by the hypoxia-inducible factor (HIF) family of transcription factors, … The small molecules that
can modulate HIF activity at … in the HIF-1α and HIF-2α transactivating domains than the DNA-…

… Hypoxia-inducible factor 1 (HIF-1) activates the transcription of … We analyzed HIF-1α
transactivation function in HeLa cells expressing … However, the effects of modulating PKA activity …

… The modulation of HIF‑1α can reduce sorafenib … the transcription factor hypoxia-inducible
factor (HIF) enables cancer cells to adapt to the hypoxic environment via the transactivation of …

… , and these may further modulate specific aspects of the HIF … This factor was termed
hypoxia-inducible factor 1 and is a … transactivation domain (CTAD) of HIF-α by factor inhibiting HIF-…

… The hypoxia-inducible factor (HIF) system orchestrates … HIF is an α/β-heterodimeric
transcription factor that regulates the … domain (CTAD) of HIFα isoforms, as catalyzed by factor-…

… Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that … to pathogens through the
modulation of immune cell functions… HIF-1α contains two transactivation domains: the N-terminal …

… activation of the transcription factor hypoxia-inducible factor (HIF). … two transactivation domains:
the N-terminal transactivation … interactions amenable to modulation of all HIF complexes. …