Continuous soy isoflavones exposure from weaning to maturity induces downregulation of ovarian steroidogenic factor 1 gene expression and corresponding …

W Wang, Y Sun, Y Guo, P Cai, Y Li, J Liu, G Cai… - Toxicology Letters, 2017 - Elsevier
… ) decrease in key transcription factor steroidogenic factor-1 (SF-1) … To confirm the CpG island
methylation levels of the SF-1 … endometriotic tissue are hypomethylated and are associated …

Analysis of the methylation profiles of the steroidogenic factor-1 (SF-1) gene in peritoneal and ovarian endometriosis

NG Annisa, RR Febri, T Kinasih… - Journal of Physics …, 2018 - iopscience.iop.org
Steroidogenic Factor-1 (SF-1) is a transcriptional factor involved in … Transcriptional activation
of steroidogenic factor-1 by hypomethylation of the 5' CpG island in endometriosis J. Clin. …

Epigenetic regulation of aldosterone synthase gene by sodium and angiotensin II

Y Takeda, M Demura, F Wang… - Journal of the …, 2018 - Am Heart Assoc
5, group A, member 1 (NR5A1) (steroidogenic factor 1 [SF1]) … in the promoter region of
CYP11B2 was hypomethylated in … are not always stable in CpG island promoters. However, very …

Pregnancy and lactation differentially modify the transcriptional regulation of steroidogenic enzymes through DNA methylation mechanisms in the hippocampus of …

MF Rossetti, J Varayoud, GP Lazzarino… - Molecular and cellular …, 2016 - Elsevier
… of the hypermethylation age-associated state of steroidogenic-… No CpG Island was found in
this promoter region; however, … is necessary for the transcriptional activation of the principal …

DNA hypomethylation of the nuclear receptor subfamily 5 (NR5A1) gene promoter is associated with endometriosis among women in north west of Iran

S Larki, M Maleki - Jorjani Biomedicine Journal, 2018 - goums.ac.ir
… The protein encoded by this gene is a transcriptional activator … names such as SF-1 (steroidogenic
factor 1) and Ad4BP. It is a … Hypermethylation of CpG islands may inhibit transcription

Epigenetic changes of the Cyp11a1 promoter region in granulosa cells undergoing luteinization during ovulation in female rats

M Okada, L Lee, R Maekawa, S Sato, T Kajimura… - …, 2016 - academic.oup.com
… -1) (−133 to −125 bp), and steroidogenic factor 1 (SF-1)/liver receptor … (0 h), 5 CpGs in the
proximal region were hypomethylated, … (Figure 5), we investigated whether transcription factors …

[HTML][HTML] Molecular and epigenetic control of aldosterone synthase, CYP11B2 and 11-Hydroxylase, CYP11B1

Y Takeda, M Demura, M Kometani… - International Journal of …, 2023 - mdpi.com
… (NBRE-1), activating transcription factor 1 (ATF1), or CRE-… syndrome, hypomethylation of
a portion of the CpG site of the … CpG islands are reported to be present in rodents but absent …

[HTML][HTML] Vimentin-mediated steroidogenesis induced by phthalate esters: involvement of DNA demethylation and nuclear factor κB

Y Li, Y Hu, C Dong, H Lu, C Zhang, Q Hu, S Li, H Qin… - PLoS …, 2016 - journals.plos.org
… these sequences were located in the CpG islands (S2A Fig). … Further, hypermethylation
treatment by SAM dramatically … of NF-κB in the transcriptional activation of vimentin. The pGL3-…

Impact of Lactational Exposure to Polychlorinated Biphenyl Causes Epigenetic Modification and Impairs Sertoli Cells Functional Regulators in F1 Progeny

E Sugantha Priya, T Sathish Kumar, P Raja Singh… - Reproductive …, 2018 - Springer
… Unmethylated CpG islands are targets of transcription factors … as steroidogenic factor 1
(SF1), upstream stimulatory factor 1 (… exposure of DEHP induced hypermethylation in SF1 and …

Significant association of cyp19a promoter methylation with environmental factors and gonadal differentiation in olive flounder Paralichthys olivaceus

Z Fan, Y Zou, S Jiao, X Tan, Z Wu, D Liang… - … and Physiology Part A …, 2017 - Elsevier
… And de novo DNA methylation in cyp19a promoter CpG island (CpGI) region was induced
at late … Nr5a2 can bind to hypomethylated promoter of cyp19a and activate its transcription, …