Estrogen-and progesterone (P4)-mediated epigenetic modifications of endometrial stromal cells (EnSCs) and/or mesenchymal stem/stromal cells (MSCs) in the …

D Szukiewicz, A Stangret, C Ruiz-Ruiz… - Stem Cell Reviews and …, 2021 - Springer
… Epigenetic alterations regarding transcription factors of estrogen and P4 signaling pathways
in MSCs are robust in endometriotic tissue. Thus, perspectives for the future may include …

Regulation of the telomerase reverse transcriptase subunit through epigenetic mechanisms

KA Lewis, TO Tollefsbol - Frontiers in genetics, 2016 - frontiersin.org
… Normal human somatic cells have a non-methylated/hypomethylated CpG island within the
… in the transcriptional activation of SMYD3. The presence of E2F-1 activates SMYD3, which …

Examination of Methylation Status and Occupancy of DNA Methylation Modifying Proteins on Regulatory Regions of the DAX-1 Gene

CP Riedstra - 2021 - repository.usfca.edu
… Figure 1.3 Locations of hyper and hypomethylation in … Figure 3.10 Sequence alignment
of CpG island in the DAX-1 … the transcriptional start site, specifically targeting the CpG island

Dnmt1/Tet2-mediated changes in Cmip methylation regulate the development of nonalcoholic fatty liver disease by controlling the Gbp2-Pparγ-CD36 axis

J Lee, JH Song, JH Park, MY Chung, SH Lee… - … & Molecular Medicine, 2023 - nature.com
… The methylation status of CpG islands of the Cmip intron 1 … , and observed its transcriptional
activation of target genes. … 10 CpG sites in Cmip intron 1 were perfectly hypomethylated

Epigenetic regulation in metabolic diseases: mechanisms and advances in clinical study

YL Wu, ZJ Lin, CC Li, X Lin, SK Shan, B Guo… - … and Targeted Therapy, 2023 - nature.com
… on the CpG islands. … transcriptional activation-related methylations exhibited on histone H3
on lysine 4 (H3K4), H3K36, H3K79, and arginine 17 (H3R17). On the contrary, transcriptional

The role of epigenetic changes in preeclampsia

A Kamrani, I Alipourfard, H Ahmadi‐Khiavi… - Biofactors, 2019 - Wiley Online Library
… tissue specific genes, have CpG islands and are expressed in a … and hypermethylation
happens in CpGs located in the … with increase in the transcriptional activation of related genes.68 …

[HTML][HTML] Role of the bHLH transcription factor TCF21 in development and tumorigenesis

CFP Lotfi, BS Passaia, JL Kremer - Brazilian Journal of Medical and …, 2021 - SciELO Brasil
… are associated with methylation of CpG islands. There is also … downregulated primarily by
DNA hypermethylation, rather than … of steroidogenic factor 1 (SF1/NR5A1), decreasing SF-1 …

Role of DNA methylation in the resistance to therapy in solid tumors

S Romero-Garcia, H Prado-Garcia… - Frontiers in …, 2020 - frontiersin.org
… , transcriptional activation by hypomethylation is observed in proto-oncogenes. Hypomethylation
may … Most DNAm changes in cancer occur in both CpG islands and CpG island shores, …

Recent insights on the genetics and epigenetics of endometriosis

B Borghese, KT Zondervan, MS Abrao… - Clinical …, 2017 - Wiley Online Library
… , or open seas according to the distance from the CpG islands) as well as in various regions
… the GATA transcription factors, especially GATA6, as well as SF1 (steroidogenic factor 1), …

Epithelial mutations in endometriosis: link to ovarian cancer

SE Bulun, Y Wan, D Matei - Endocrinology, 2019 - academic.oup.com
… expression of nuclear receptors [eg, steroidogenic factor-1 (SF1) and estrogen receptor (ER)–β…
A CpG island in the promoter of the ERβ gene (ESR2) is hypomethylated in endometriotic …