… human suspension packaging cell line producing ecotropic retroviral MLV (PVC-211) vectors efficiently transducing murine hematopoietic stem and progenitor cells

Y van Heuvel, K Berg, T Hirch, K Winn… - Journal of virological …, 2021 - Elsevier
… Despite their inability to transduce non-cycling cells, retroviral vectors derived from MLV …
(LTRs; dotted arrows) of murine embryonic stem cell virus (MSCV) and the packaging signal Ψ …

Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells

FK Geis, M Galla, D Hoffmann, J Kuehle, D Zychlinski… - Retrovirology, 2017 - Springer
… suitable alternative to embryonic stem cells (ESC) for the study of cellular differentiation and
… tested retroviral vectors were observed. Notably, both GV and LV exhibited low transduction

[HTML][HTML] Ecotropic HIV-1 vectors pseudotyped with R-peptide-deleted envelope protein variants reveal improved gene transfer efficiencies

N Tschorn, C Söhngen, K Berg, J Stitz - Virology, 2022 - Elsevier
… To elevate gene transduction, retroviral vectors are commonly … HSCs and progenitor cells
mediated by ecotropic MLV vectors … To improve gene transduction efficiencies, retroviral Env …

Construction of a replication-competent retroviral vector for expression of the VSV-G envelope glycoprotein for cancer gene therapy

SY Jin, YT Jung - Archives of Virology, 2020 - Springer
Transduction of human hematopoietic stem cells with GALV … 1, the ‘ecotropic envelope
glycoprotein’-encoding gene from … retroviral vectors in transducing human cancer cell lines. Since …

Retroviral vectors in gene therapy

C Gopinath, TJ Nathar, EJR Nelson - Gene and Cell Therapy: Biology and …, 2018 - Springer
… , cationic amino acid transporter CAT1 for ecotropic MLV, T cell surface marker CD4 for HIV1,
and … the transduction efficiency of hematopoietic stem cells (HSCs) in mouse models [70]. …

Highly efficient transfer of chromosomes to a broad range of target cells using Chinese hamster ovary cells expressing murine leukemia virus-derived envelope …

T Suzuki, Y Kazuki, M Oshimura, T Hara - PLoS One, 2016 - journals.plos.org
cells, including embryonic stem cells. Moreover, retro-MMCT enabled efficient transfer of MAC
to recipient cells derived from humans… represent CHO cells transduced with ecotropic and …

Retroviral vectors

WH Günzburg, B Salmons - Gene Therapy, 2020 - taylorfrancis.com
… if the PBS of murine embryonic stem cell virus and the U3 … a chemically modified ecotropic
MoMLV to infect human hepatocytes. … The H9 cells transduced with the retrovirus vector were …

Pseudotyped lentiviral vectors: one vector, many guises

AV Joglekar, S Sandoval - Human gene therapy methods, 2017 - liebertpub.com
… Viruses can be repurposed into viral vectors to achieve … vectors can transduce human
CD34+ hematopoietic stem/… cells such as murine embryonic stem cells, human HSCs, and …

Development of transposon and retrovirus-derived vectors for the rapid establishment of efficient producer cell lines

N Tschorn - 2023 - repo.uni-hannover.de
… this, viral vectors were equipped with the ecotropic envelope … lines in relation to retroviral
gene transduction is provided in … optimize transposon vectors and retroviral vectors enabling …

Pluripotent stem cell-based gene therapy approach: Human de novo synthesized chromosomes

SA Sinenko, SV Ponomartsev, AN Tomilin - Cellular and Molecular Life …, 2021 - Springer
viral vectors were used for the treatment of several different … pluripotent embryonic stem
cells (ESCs) from the inner cellcells, were purified and transduced into human cells. Positive …