Implantation of glial cell line-derived neurotrophic factor-expressing adipose tissue-derived stromal cells in a rat Parkinson's disease model

R Xu, J Wu, L Lang, J Hu, H Tang, J Xu… - Neurological …, 2020 - Taylor & Francis
ecotropic retroviral receptor followed by an ecotropic retrovirus allowed all ADSCs to be
transduced [… indicated that lentiviral transduction does not alter the multipotent stem cells, which …

[引用][C] Forming megakaryocytes from murine-induced pluripotent stem cells by the inducible overexpression of supporting factors

F Schenk, DVM Ute Modlich - 2020

TGF-β signaling in stem cell regulation

W Li, W Wei, S Ding - TGF-β Signaling: Methods and Protocols, 2016 - Springer
embryonic stem cells (hESCs) and human induced … with mouse Slc7a1 ORF (murine ecotropic
retroviral receptor). … used to transduce 20–30 % confluence human fibroblasts CRL2097 …

[HTML][HTML] New α-and SIN γ-retrovectors for safe transduction and specific transgene expression in pancreatic β cell lines

O Albagli, A Maugein, L Huijbregts, D Bredel… - BMC …, 2019 - Springer
… harmless viral vectors for stable transduction and specific transgene expression in β cells. …
of this method to transfer the ecotropic receptor (mCAT-1) to human β cells [14]. The second …

Gene therapy comes of age

CE Dunbar, KA High, JK Joung, DB Kohn, K Ozawa… - Science, 2018 - science.org
… of viral vectors, adoptive transfer of genetically engineered T cells or hematopoietic stem
cells… Despite relatively low HSC transduction efficiencies with γ-retroviral vectors, gene-modified …

Therapeutic applications of viral vectors

P Lowenstein, D Stone, A David… - Genetically …, 2023 - taylorfrancis.com
retroviral vectors to easily transduce cells in vitro has led to the development of ex vivo
therapeutic strategies, whereby retroviral vectors … or haematopoietic stem cells, retroviral vectors

Genetic modification of T cells with chimeric antigen receptors: a laboratory manual

V Golumba-Nagy, J Kuehle, H Abken - Human Gene Therapy …, 2017 - liebertpub.com
retroviral vectors require cell division of target cells with the consequence that preferentially
cycling T cells are transduced… allow transduction of murine cells using an ecotropic envelope …

[HTML][HTML] Identifying cancer driver genes using replication-incompetent retroviral vectors

VM Bii, GD Trobridge - Cancers, 2016 - mdpi.com
vectors require membrane bound receptors for cellular entry, however the use of an envelope
pseudotype allows retroviral vectors to transduce many different cellstem cell (HSC) gene …

[HTML][HTML] Conversion of human and mouse fibroblasts into lung-like epithelial cells

AP Wong, S Shojaie, Q Liang, S Xia, M Di Paola… - Scientific reports, 2019 - nature.com
… The CA1 human embryonic stem cell line was approved for use by the … were seeded at 1
× 10 5 cells/well onto 6 well plates and transduced once with the retroviral vectors and 8 μg/ml …

Pluripotent stem cell-based gene therapy approach: Human de novo synthesized chromosomes

SA Sinenko, SV Ponomartsev, AN Tomilin - Cellular and Molecular Life …, 2021 - Springer
viral vectors were used for the treatment of several different … pluripotent embryonic stem
cells (ESCs) from the inner cellcells, were purified and transduced into human cells. Positive …