[HTML][HTML] An optimized GD2-targeting retroviral cassette for more potent and safer cellular therapy of neuroblastoma and other cancers

S Thomas, K Straathof, N Himoudi, J Anderson… - PLoS One, 2016 - journals.plos.org
human T-cells were transduced with equal titers of retroviral … (retroviral vectors with both
SAR and CHS4 were generated … This is consistent with results in adipose tissue stem cells in …

[PDF][PDF] POGZ is required for silencing mouse embryonic β-like hemoglobin and human fetal hemoglobin expression

B Gudmundsdottir, KO Gudmundsson, KD Klarmann… - Cell reports, 2018 - cell.com
… is expressed in normal mouse hematopoietic stem and progenitor cells (HSPCs), with the …
FL cells were harvested at E16.5 and transduced with a control retrovirus or retroviral vector

Blockade of senescence‐associated micro RNA‐195 in aged skeletal muscle cells facilitates reprogramming to produce induced pluripotent stem cells.

H Kondo, HW Kim, L Wang, M Okada, C Paul… - … Cell, 2016 - Wiley Online Library
… The use of embryonic stem cells (ESCs) affords a feasible … in the later stage of cultured cells
after transduction of miR-195 inhibitor, … with the ecotropic packaging plasmid pCL-Eco (4 μg) …

[图书][B] Innate Immune Modulation and Lentiviral Vector Modification to Improve Anti-HIV Gene Therapy

ST Ozog - 2019 - search.proquest.com
… block to efficient transduction was due to vector inhibition by the … Lentiviral vectors and
ɣ-retroviral vectors both contain an RNA … leukemia virus type I (HTLV-1) and ecotropic MLV 76. …

[HTML][HTML] Sox2 and Pax6 play counteracting roles in regulating neurogenesis within the murine olfactory epithelium

AI Packard, B Lin, JE Schwob - PLoS One, 2016 - journals.plos.org
… the function of transduced progenitor cells. Both TFs when … , env genes provide ecotropic
packaging of the viral genome, after which … We used retroviral vectors encoding Sox2 and Pax6 …

[PDF][PDF] IND-enabling studies for a clinical trial to genetically program a persistent cancer-targeted immune system

CS Seet, A Montel-Hagen, GM Crooks, RP Hollis… - authors.library.caltech.edu
… of the ecotropic RV-NY-ESO-1 TCR retroviral vector, we transduced murine T cells from
HLA-A2/Kb … Finally, we showed that the transduced and in vitro-cultured stem cells were able to …

[PDF][PDF] Role of Sox2 and its binding partners in the neural induction of human embryonic stem cells

S Zhang - 2016 - core.ac.uk
… Neural differentiation from human embryonic stem cells (hESCs) provides a promising source
for cell replacement therapies. However, the mechanisms underlying the control of neural …

[HTML][HTML] Development of CAR-T cell persistence in adoptive immunotherapy of solid tumors

J Fan, JK Das, X Xiong, H Chen, J Song - Frontiers in Oncology, 2021 - frontiersin.org
… E packaging cells using the ecotropictransduce primary CD8 + T cells that permit the
expression of multiple genes, we used a T2A sequence to generate multicistronic retroviral vectors

Reprogramming cancer cells: overview & current progress

KL Lim, HK Teoh, PF Choong, HX Teh… - Expert opinion on …, 2016 - Taylor & Francis
transduced first with doxycycline-inducible lentiviral vectors … reprogrammed with ecotropic
retrovirus expressing OSKM … reprogramming of cancer cells using viral vectors to deliver the …

Calreticulin affects hematopoietic stem/progenitor cell fate by impacting erythroid and megakaryocytic differentiation

S Salati, Z Prudente, E Genovese… - Stem Cells and …, 2018 - liebertpub.com
… the ecotropic Phoenix and amphotropic GP+envAm12 cells, … To this end, we constructed
the LCALRIDN retroviral vectorretroviral vectors to the erythroblastic progeny of transduced