… Grandisin have high trypanocidal activity against the tripomastigote forms of … is the
tetrahydrofuran lignans isolated from Virola surinamensis twigs and Piper solmsianum …

… the detection of secondary plant metabolites with trypanocidal activity and have been performed
… The aim of the present study was to determine the trypanocidal activity of a new lignan …

… leaves, branches and inflorescences showed the presence … Piper solmsianum. The
confirmation of the corrected configuration among aryls and methyl groups presented in THF lignans …

… known as lignins and dimmers such as lignans [21]. According to … in the inflorescences,
once many authors described the use of aerial parts (16 citations). To date, none tetrahydrofuran-…

… Piper is the one of the most important genera of this family and its species show similar …
solmsianum, VO obtained from the leaves of P. amalago and P. cernuum, hexanic phase …

… subscutatum, tetrahydrofuran lignans are typical secondary … discovered in the Brazilian
species Piper solmsianum [42]. (–)-… On the other hand, three highly active trypanocidal lignans …

… of grandisin, a lignan extracted from Piper solmsianum, was evaluated … tetrahydrofuran
lignan grandisin, isolated from Virola and Piper species, presents antimalarial and trypanocidal …

… solmsianum contain tetrahydrofuran lignans, and prenylated benzoic acids are found in …
solmsianum also produces dillapiole as seedlings, but adults contain tetrahydrofuran lignan (12)…

… Trypanocidal tetrahydrofuran lignans from inflorescences of Piper solmsianum. Phytochemistry,
64 (2), 667–670. Meotti, FC; Ardenghi, JV; Pretto, JB; Souza, MM; Moura, JD; Junior, AC; …

… Thus in the past decade, a huge number of trypanocidal natural compounds have … lignans
of the tetrahydrofuran and aryltetralin types are also found in this plant species, whose lignans …