Enhanced antiglioblastoma efficacy of neovasculature and glioma cells dual targeted nanoparticles
L Lv, Y Jiang, X Liu, B Wang, W Lv, Y Zhao… - Molecular …, 2016 - ACS Publications
… In this study, we investigated a tumor cells and neovasculature combination targeted strategy
of nanocarrier, which was validated to enhance the antiglioma efficacy. The acquired PC-…
of nanocarrier, which was validated to enhance the antiglioma efficacy. The acquired PC-…
[HTML][HTML] Cyclic-RGDyC functionalized liposomes for dual-targeting of tumor vasculature and cancer cells in glioblastoma: An in vitro boron neutron capture therapy …
… of 10 B to the target. Integrins αvβ3 are transmembrane … glioblastoma cells and its
neovasculature. In this study, a novel approach to dual-target glioblastoma vasculature and tumor …
neovasculature. In this study, a novel approach to dual-target glioblastoma vasculature and tumor …
Tumor microenvironment and angiogenic blood vessels dual-targeting for enhanced anti-glioma therapy
Q Hu, T Kang, J Feng, Q Zhu, T Jiang… - … applied materials & …, 2016 - ACS Publications
… (11, 46-48) By taking advantage of BBB/glioma and neovasculature/glioma dual-targeting …
To evaluate the tumor blood vessel and tumor cells dual-targeting effects, HUVEC cells with …
To evaluate the tumor blood vessel and tumor cells dual-targeting effects, HUVEC cells with …
EGFR/EGFRvIII dual-targeting peptide-mediated drug delivery for enhanced glioma therapy
J Mao, D Ran, C Xie, Q Shen, S Wang… - ACS applied materials & …, 2017 - ACS Publications
… -based drug delivery. Micelles are designed to specifically penetrate the BBTB and target
neovasculature, VM, tumor cells, … a superior targeting ability in vivo compared with l-AE-micelle. …
neovasculature, VM, tumor cells, … a superior targeting ability in vivo compared with l-AE-micelle. …
Nanoparticle-based co-delivery of siRNA and paclitaxel for dual-targeting of glioblastoma
… RGD could target tumor cells, … in glioma cells and the tumor vasculature with a minimal
expression on a normal resting vascular bed [Citation24], thus, our dual-target TGN/RGD delivery …
expression on a normal resting vascular bed [Citation24], thus, our dual-target TGN/RGD delivery …
Combined tumor-and neovascular-“dual targeting” gene/chemo-therapy suppresses tumor growth and angiogenesis
B Xu, Q Jin, J Zeng, T Yu, Y Chen, S Li… - … Applied Materials & …, 2016 - ACS Publications
… The promising drug delivery systems for tumor cells and neovasculature dual targeting
delivery might be more advantageous for promoting particle penetration and improving treatment …
delivery might be more advantageous for promoting particle penetration and improving treatment …
[HTML][HTML] Application of dual targeting drug delivery system for the improvement of anti-glioma efficacy of doxorubicin
Z Sun, X Yan, YB Liu, L Huang, C Kong, X Qu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… The prepared nano-vehicle system could not only kill tumor cells directly, but also blocking
… dual targeting nanoparticles prepared in this study could be used for the therapy of glioma. …
… dual targeting nanoparticles prepared in this study could be used for the therapy of glioma. …
An update on dual targeting strategy for cancer treatment
… delivery of therapeutic agents to cancer cells while minimizing drug toxicity to normal cells
and off-targeting … of highly leaky vasculature and low lymphatic drainage Both are typical in …
and off-targeting … of highly leaky vasculature and low lymphatic drainage Both are typical in …
Neovasculature and circulating tumor cells dual-targeting nanoparticles for the treatment of the highly-invasive breast cancer
J Yao, J Feng, X Gao, D Wei, T Kang, Q Zhu, T Jiang… - Biomaterials, 2017 - Elsevier
… In summary, the tumor neovasculature and CTCs dual-targeting drug delivery system
exhibited … modality holds great potential for the treatment of the highly-invasive breast cancer. …
exhibited … modality holds great potential for the treatment of the highly-invasive breast cancer. …
Dual-targeted nanomedicines for enhanced tumor treatment
… in DU145 and PC3 prostate cancer cells, respectively, than … expressing tumor vasculature
and Tf then improves the cellular … BBB and glioma targeting are required in glioma therapy. …
and Tf then improves the cellular … BBB and glioma targeting are required in glioma therapy. …