[HTML][HTML] Tumor-associated macrophages: therapeutic targets for skin cancer

T Fujimura, Y Kambayashi, Y Fujisawa, T Hidaka… - Frontiers in …, 2018 - frontiersin.org
… in each differential stage, leading to the suppression of tumor growth. Because the …
various tumor-infiltrating lymphocytes, TAMs can serve as targets for cancer immunotherapy…

Cancer stem cells (CSCs) in cancer progression and therapy

M Najafi, B Farhood… - Journal of cellular …, 2019 - Wiley Online Library
differentiation of CSCs. When the cells are committed to differentiation, they cannot initiate
tumor growth … of CD51 could be a therapeutic target for restricting progression of prostate …

[HTML][HTML] New mechanisms of tumor-associated macrophages on promoting tumor progression: recent research advances and potential targets for tumor …

Q Guo, Z Jin, Y Yuan, R Liu, T Xu, H Wei… - Journal of immunology …, 2016 - hindawi.com
… macrophages are not stably differentiated subsets and can … an ideal therapeutic target for
blocking tumor progression after … 4T1 breast cancer growth by modulating TAM differentiation […

Understanding the role of structural integrity and differential expression of integrin profiling to identify potential therapeutic targets in breast cancer

V Das, G Kalyan, S Hazra, M Pal - Journal of Cellular …, 2018 - Wiley Online Library
… In this review article, we emphasize on the differential expression of integrins structure,
interactions of different motifs or domains, and their function in breast cancer progression. …

[HTML][HTML] Androgen receptor (AR) cistrome in prostate differentiation and cancer progression

F Wang, HK Koul - American Journal of Clinical and Experimental …, 2017 - ncbi.nlm.nih.gov
… categories of AR therapy resistance: the first … therapy, and the second one involves tumor
progression despite blockade of AR activity. As such AR remains the most attractive drug target

SNAIL is a key regulator of alveolar rhabdomyosarcoma tumor growth and differentiation through repression of MYF5 and MYOD function

K Skrzypek, A Kusienicka, E Trzyna, B Szewczyk… - … Death & Disease, 2018 - nature.com
… In conclusion, the induction of ARMS differentiation by SNAIL silencing leads to the … of
tumor growth, suggesting that SNAIL may be a novel target for differentiation-based therapies in …

[HTML][HTML] … SERMs in human cancer lines of different origin and its predictive molecular docking studies of key target genes involved in cancer progression and treatment …

S Lakshmi, A Shanitha, S Dv, R Bs, R Saikant… - Current Research in …, 2022 - Elsevier
… clinically used four SERMS in twenty six cancer cell lines of different origin using Adriamycin
… selected target/ligand with respect to tumor progression, development, treatment responses …

Cancer: a problem of developmental biology; scientific evidence for reprogramming and differentiation therapy

S Sell, A Nicolini, P Ferrari, PM Biava - Current drug targets, 2016 - ingentaconnect.com
cancer growth, these cancer stem cells seem to be a likely target for novel strategies for
prostate cancer therapy. … prostate cancer cells caused growth inhibition and rapid apoptosis in …

Cancer-testis antigens: Unique cancer stem cell biomarkers and targets for cancer therapy

O Gordeeva - Seminars in cancer biology, 2018 - Elsevier
… associated with cancer transformation and abnormal differentiation of … cancer treatment
strategy. However, for effective destruction of cancer cells initiating and supporting tumor growth

Wnt signaling in colorectal cancer: pathogenic role and therapeutic target

H Zhao, T Ming, S Tang, S Ren, H Yang, M Liu, Q Tao… - Molecular cancer, 2022 - Springer
… promotes cancer stem cell renewal, cell proliferation and differentiation, … target genes provides
a reasonable explanation for how Wnt allows CSC mutations during cancer progression. It …