[PDF][PDF] Multi-stage differentiation defines melanoma subtypes with differential vulnerability to drug-induced iron-dependent oxidative stress
… therapeutic approach to target the differentiation plasticity of melanoma cells to increase the
efficacy of targeted and immune therapies. … during treatment and upon disease progression …
efficacy of targeted and immune therapies. … during treatment and upon disease progression …
Exploiting differential RNA splicing patterns: a potential new group of therapeutic targets in cancer
N Jyotsana, M Heuser - Expert opinion on therapeutic targets, 2018 - Taylor & Francis
… differential expression of splice variants that are frequently linked to cancer progression,
metastasis and therapy … of alternative splicing events in cancer progression is known for few of …
metastasis and therapy … of alternative splicing events in cancer progression is known for few of …
Signaling pathways in cancer-associated fibroblasts and targeted therapy for cancer
F Wu, J Yang, J Liu, Y Wang, J Mu, Q Zeng… - … and Targeted Therapy, 2021 - nature.com
… during the cancer progression and have the potential to be targeted for anticancer therapy.
… signals mediating crosstalk of CAFs with cancer cells and its related targets or trials. Further, …
… signals mediating crosstalk of CAFs with cancer cells and its related targets or trials. Further, …
Tumor microenvironment components: Allies of cancer progression
PIR Franco, AP Rodrigues, LB de Menezes… - … -Research and Practice, 2020 - Elsevier
… targets in the study of tumor biology and oncology therapies [… The stem cell differentiation
mechanism is highly controlled … to tumor progression enable specific therapeutic strategies for …
mechanism is highly controlled … to tumor progression enable specific therapeutic strategies for …
Tumor-associated macrophages: an accomplice in solid tumor progression
Y Chen, Y Song, W Du, L Gong, H Chang… - Journal of biomedical …, 2019 - Springer
… can be used as therapeutic targets of solid tumor in clinics. The therapeutic strategies include
… The differential contributions of iTreg and nTreg to the immunosuppressive properties of …
… The differential contributions of iTreg and nTreg to the immunosuppressive properties of …
… , radionecrosis, inflammation or true tumor progression? Challenges associated with glioblastoma response assessment in an evolving therapeutic landscape
… tumor response to therapy with the goal of both understanding biological changes within the
… promising methods for differentiation of tumor progression from recurrent disease based on …
… promising methods for differentiation of tumor progression from recurrent disease based on …
Tumor microenvironment as a therapeutic target in cancer
Y Xiao, D Yu - Pharmacology & therapeutics, 2021 - Elsevier
… to play critical roles in tumor progression and therapeutic responses, attention has been …
exclusive categories marked by discrete activation or differentiation status (polarization), has …
exclusive categories marked by discrete activation or differentiation status (polarization), has …
Tumor-derived exosomes and their role in cancer progression
TL Whiteside - Advances in clinical chemistry, 2016 - Elsevier
… therapy suggest that tumor-derived exosomes are critical … changes in target cells that favor
tumor progression. Numerous … tumor stroma, driving neovascularization, cell differentiation …
tumor progression. Numerous … tumor stroma, driving neovascularization, cell differentiation …
Transforming growth factor-β: A therapeutic target for cancer
S Haque, JC Morris - Human vaccines & immunotherapeutics, 2017 - Taylor & Francis
… cancer progression. In later stages TGF-β plays a key role in promoting tumor progression
… and endochondral tissue highlighting its role in growth and tissue differentiation. TGF-β2 is …
… and endochondral tissue highlighting its role in growth and tissue differentiation. TGF-β2 is …
[HTML][HTML] Metabolic cooperation and competition in the tumor microenvironment: implications for therapy
… for identifying suitable targets for developing newer therapeutic approaches. … decide
the fate of the tumor growth by affecting the functions and differentiation of various subsets of …
the fate of the tumor growth by affecting the functions and differentiation of various subsets of …