… GSCs and their differentiated glioblastoma cell (DGC) progeny. We found that DGCs accelerated
GSC tumor growth. DGCs … immune responses, and resistance to cytotoxic therapies ( …

… and multi-lineage differentiation to drive tumour growth and … , conventional cancer treatments
target the bulk of the tumour … the cancer progression contributing to therapy resistance, …

… The goal of this review is to examine and discuss in deep … Lastly, we explore the efforts to
target the lactate production … and M2 macrophage differentiation, which in turn promoted tumor …

… target CSCs, differentiation therapy attracts increasing attention, inducing CSCs to bulk tumor
… inhibited the tumor progression via inducing OS cell differentiation and apoptosis, whereas …

… Since cancer stem cells (CSCs) were first … therapeutic targets for cancer therapy. These
cells have self-renewal capacity and differentiation potential and contribute to multiple tumor …

… could be the potential downstream target for clopidogrel therapy. … treatment at a daily
dosage of 5 mg/kg for three weeks induced tumor cell differentiation and inhibited tumor growth. …

… in each differential stage, leading to the suppression of tumor growth. Because the …
various tumor-infiltrating lymphocytes, TAMs can serve as targets for cancer immunotherapy…

… of mitochondrial injury and this can convert differentiated cells into proliferating malignant
cells [10]. … Thus, the use of tumor glycolysis as a potential target for cancer therapy is the most …

… stimulate cancer cell proliferation and enhance cancer growth (… and cancer, the targeting of
TAM recruitment and differentiation … targets for cancer prevention and therapy. A combination …

… and tumor progression becomes more evident and new existing therapeutic approaches can
… and nuclear targets regulating cell proliferation, survival, differentiation, apoptosis and in …