[HTML][HTML] Androgen receptor (AR) cistrome in prostate differentiation and cancer progression

F Wang, HK Koul - American Journal of Clinical and Experimental …, 2017 - ncbi.nlm.nih.gov
… categories of AR therapy resistance: the first … therapy, and the second one involves tumor
progression despite blockade of AR activity. As such AR remains the most attractive drug target

Survivin: a unique target for tumor therapy

H Garg, P Suri, JC Gupta, GP Talwar, S Dubey - Cancer cell international, 2016 - Springer
… , absent in most normal, terminally differentiated tissues but upregulated in a variety of … may
perform contrasting functions in tumor progression and response to therapy [28]. Presence of …

[HTML][HTML] Targeting glutaminolysis: new perspectives to understand cancer development and novel strategies for potential target therapies

Z Wang, F Liu, N Fan, C Zhou, D Li, T Macvicar… - Frontiers in …, 2020 - frontiersin.org
cancer cells strongly supports tumor growth and progression, which in turn could encourage
the investigation for metabolic targeted therapy … explained by the differential expression of …

The emerging role of targeted therapies for advanced well-differentiated gastroenteropancreatic neuroendocrine tumors

JM Cloyd, B Konda, MH Shah… - Expert Review of Clinical …, 2019 - Taylor & Francis
therapy. SSAs may also be used as a bridge to more effective systemic therapies when the
rate of disease progression … viruses to target tumor cells and stimulate anti-tumor immune …

Hypoxia-inducible factors: master regulators of cancer progression

L Schito, GL Semenza - Trends in cancer, 2016 - cell.com
therapies target well-oxygenated and proliferating cancer cells, whereas there are no approved
therapies that target hypoxic cancer … factor driving cancer progression. In this review, our …

SNAIL is a key regulator of alveolar rhabdomyosarcoma tumor growth and differentiation through repression of MYF5 and MYOD function

K Skrzypek, A Kusienicka, E Trzyna, B Szewczyk… - … Death & Disease, 2018 - nature.com
… In conclusion, the induction of ARMS differentiation by SNAIL silencing leads to the … of
tumor growth, suggesting that SNAIL may be a novel target for differentiation-based therapies in …

Neutrophil diversity and plasticity in tumour progression and therapy

S Jaillon, A Ponzetta, D Di Mitri, A Santoni… - … Reviews Cancer, 2020 - nature.com
… Here, we review current evidence for the role of neutrophils in tumour progression and …
tissue cues and cancer progression (Box 2). Neutrophil differentiation and maturation trajectories …

TGF-β family signaling in tumor suppression and cancer progression

J Seoane, RR Gomis - Cold Spring Harbor perspectives …, 2017 - cshperspectives.cshlp.org
… of the TGF-β pathway as a therapeutic target against cancer be evaluated. … in cancer
progression and metastasis by suppressing self-renewal and promoting cancer cell differentiation. …

[HTML][HTML] … SERMs in human cancer lines of different origin and its predictive molecular docking studies of key target genes involved in cancer progression and treatment …

S Lakshmi, A Shanitha, S Dv, R Bs, R Saikant… - Current Research in …, 2022 - Elsevier
… clinically used four SERMS in twenty six cancer cell lines of different origin using Adriamycin
… selected target/ligand with respect to tumor progression, development, treatment responses …

Src family kinases as therapeutic targets in advanced solid tumors: what we have learned so far

S Martellucci, L Clementi, S Sabetta, V Mattei, L Botta… - Cancers, 2020 - mdpi.com
… mechanisms involving SFKs in cancer spreading and metastasization… application as therapeutic
targets in solid cancer progression … stage, cellular differentiation, and formation of distant …