… Since the early steps of tumorigenesis, cancer and stromal cells increase the number of
TAMs in the tumor, by producing chemokines and growth factors (eg, CCL2 and CSF1) [3,66,67]. …

Background: Breast cancer (BRCA) has become the most common cancer worldwide. The
tumor … Tumor-associated macrophages (TAMs) are the primary component of tumor-infiltrating …

… In tumour stroma at all levels of the cancer progression, macrophages recruited to TME …
Tumor-associated macrophage (TAM) and angiogenesis in human colon carcinoma. Open …

… stroma supports the transition of tumor-recruited Hyal2 + MDSCs to the PD-L1 + tumor-associated
macrophages … Constant mobilization of bone marrow-derived Hyal2 + MDSCs, CAFs, …

… These findings are in line with studies on colorectal cancer and esophageal squamous cell
carcinoma where a poor prognosis correlates with TGFBI expression in tumor stroma 40,41 . …

… immune cells, tumor-associated macrophages (TAMs) are numerous in the tumor stroma and
are … During cancer invasion, the tumor stroma undergoes constant architectural changes, …

… they become polarized and are referred to as Tumor-Associated Macrophages (TAMs) 16
. TAMs suppress immune activity and promote cancer progression, which is similar to their …

… by macrophages themselves as well as by stromal and cancer … constant transformation of
the tumor microenvironment [44]. … We also investigated Tumor-Associated Macrophages (TAM) …

… CD163-positive macrophages were present in the tumor stroma in 257 cases (91%), within
tumor cell nests in 224 cases (79%), and in both compartments in 200 cases (71%). The …

… Finally, we show that cancer-associated fibroblasts are significantly outnumbered by TAMs
… Tumor-associated macrophages (TAMs) are abundant in the tumor stroma at all stages of …