… interaction between the Vibrio cholerae exotoxin (cholera toxin [CT]) … Cell subfractionation
studies on brain cortex suggested ultrastructural localization of GM1 at the plasma membrane …

… of a membrane bilayer containing the ganglioside GM1 (… as seen from the perspective of
the toxin are marked by “+” … on the CTxB−GM1 interaction in cellular plasma membrane is not …

… GM1 would incorporate correctly into the plasma membrane … in T84 cells simply because
they lack gangliosides like GM1 [… GM1 can be incorporated into the plasma membrane of cells …

… cholera. The five sugar mono-sialo ganglioside GM1 is the cell surface receptor for cholera
toxin … glycosphingolipids are located on the surface of plasma membranes and membranes of …

… using negative stain electron microscopy have shown accumulation of the cholera toxin in
all … We assayed GM1 ganglioside binding affinity and stoichiometry using ITC (Figure S1 and …

… Transmission electron microscopy confirmed that the GM1-NPs … membrane coating around
a nanoparticle core (Fig 1E). … and GM1-ganglioside is extracted from natural cell membranes. …

… the inherent membrane bending capability of cholera toxin subunit … family that multivalently
binds to GM1 and is most frequently … in the plasma membrane of live cells from single particle …

… for its cellular receptor, the GSL GM1 (reviewed in References [5,6]). Yet, much like Shiga
toxin, cholera toxin also binds to cells with … Using an advanced electron microscopy technique, …

… toxin initiates endocytosis through the interaction of the B pentamer with the GM1 ganglioside
receptor on small intestinal cells. … Recent electron microscopy analyses also confirmed that …

… The primary virulence factor of Vibrio cholerae, cholera toxin (… Scanning electron microscopy
images of the OMVs exhibited … the GM1 receptor in the lipid rafts of the host cell membrane …